State Key Laboratory of Bioelectronics, School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, China.
ACS Appl Mater Interfaces. 2024 Aug 21;16(33):43102-43113. doi: 10.1021/acsami.4c07235. Epub 2024 Aug 7.
With digital transformation and the general application of new technologies, data storage is facing new challenges with the demand for high-density loading of massive information. In response, DNA storage technology has emerged as a promising research direction. Efficient and reliable data retrieval is critical for DNA storage, and the development of random access technology plays a key role in its practicality and reliability. However, achieving fast and accurate random access functions has proven difficult for existing DNA storage efforts, which limits its practical applications in industry. In this review, we summarize the recent advances in DNA storage technology that enable random access functionality, as well as the challenges that need to be overcome and the current solutions. This review aims to help researchers in the field of DNA storage better understand the importance of the random access step and its impact on the overall development of DNA storage. Furthermore, the remaining challenges and future research trends in random access technology of DNA storage are discussed, with the goal of providing a solid foundation for achieving random access in DNA storage under large-scale data conditions.
随着数字化转型和新技术的广泛应用，数据存储面临着新的挑战，需要大规模信息的高密度加载。针对这一需求，DNA 存储技术应运而生，成为一个很有前途的研究方向。高效可靠的数据检索对于 DNA 存储至关重要，而随机存取技术的发展对于其实用性和可靠性起着关键作用。然而，对于现有的 DNA 存储技术，实现快速、准确的随机访问功能一直具有挑战性，这限制了其在工业领域的实际应用。在这篇综述中，我们总结了实现随机访问功能的 DNA 存储技术的最新进展，以及需要克服的挑战和当前的解决方案。我们希望这篇综述能够帮助 DNA 存储领域的研究人员更好地理解随机访问步骤的重要性及其对 DNA 存储整体发展的影响。此外，我们还讨论了 DNA 存储随机访问技术中存在的挑战和未来的研究趋势，旨在为在大规模数据条件下实现 DNA 存储的随机访问提供坚实的基础。
