Al-Sheikh Marwah, Ankersen Dorit Vedel, Olsen Jens, Spanggaard Maria, Peters-Lehm Charlotte T, Naimi Rahim M, Bennedsen Mette, Burisch Johan, Munkholm Pia
Department of Gastroenterology, Medical Division, Copenhagen University Hospital, North Zealand, Denmark.
EY, Copenhagen, Denmark.
J Crohns Colitis. 2025 Feb 4;19(2). doi: 10.1093/ecco-jcc/jjae120.
There are few studies on the cost-effectiveness of telemedicine for inflammatory bowel diseases. We assessed the long-term cost-effectiveness of a telemedicine solution compared to standard care (sCare), as well as its efficacy according to patient-reported outcomes (PROs).
Between 2015 and 2020, we conducted a retrospective, register-based study among patients with ulcerative colitis and Crohn's disease. Direct and indirect healthcare costs over a 5-year period were obtained from Danish registers and compared to a control group. Costs were estimated on a yearly basis from 1 year before, until 5 years after, inclusion in the trial. Patients were divided into 2 groups: those not receiving biologics (Cohort 1) and those receiving biologics (Cohort 2).
We recruited 574 patients with inflammatory bowel diseases. In Cohort 1 (61.5%), average total direct costs and total earnings per patient per year were €14 043 and €307 793, respectively, in telemedicine compared to €16 226 and €252 166, respectively, in sCare. In Cohort 2 (38.5%), average total direct costs and total earnings were €73 916 and €215 833, respectively, in telemedicine compared to €41 748 and €203 667, respectively, in sCare. PROs showed improved quality of life, which was higher in Cohort 1 than in Cohort 2. Disease activity among patients with Crohn's disease increased after Years 3 and 4 in Cohorts 1 and 2, respectively.
Telemedicine is cost-effective for patients not receiving biologics. However, treatment with biologics is more expensive for patients enrolled in telemedicine. Careful attention to PROs in telemedicine improves quality of life and could prolong the time to relapse.
关于远程医疗对炎症性肠病的成本效益研究较少。我们评估了一种远程医疗解决方案与标准护理(sCare)相比的长期成本效益,以及根据患者报告结局(PROs)得出的疗效。
2015年至2020年期间,我们对溃疡性结肠炎和克罗恩病患者进行了一项基于登记的回顾性研究。从丹麦登记处获取了5年期间的直接和间接医疗费用,并与对照组进行比较。从纳入试验前1年到纳入试验后5年,每年估计费用。患者分为两组:未接受生物制剂治疗的患者(队列1)和接受生物制剂治疗的患者(队列2)。
我们招募了574例炎症性肠病患者。在队列1(61.5%)中,远程医疗组患者每年的平均总直接成本和总收入分别为14043欧元和307793欧元,而sCare组分别为16226欧元和252166欧元。在队列2(38.5%)中,远程医疗组患者每年的平均总直接成本和总收入分别为73916欧元和215833欧元,而sCare组分别为41748欧元和203667欧元。PROs显示生活质量有所改善,队列1中的改善程度高于队列2。队列1和队列2中,克罗恩病患者的疾病活动度分别在第3年和第4年后增加。
对于未接受生物制剂治疗的患者,远程医疗具有成本效益。然而,对于参加远程医疗的患者,生物制剂治疗费用更高。在远程医疗中仔细关注PROs可改善生活质量,并可能延长复发时间。