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通过应用显示省略对象的决策分析模型(DAMWOOD)来提高决策模型的透明度。

Improving Transparency of Decision Models Through the Application of Decision Analytic Models with Omitted Objects Displayed (DAMWOOD).

机构信息

Institute of Health Economics, Edmonton, Canada.

Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.

出版信息

Pharmacoeconomics. 2024 Nov;42(11):1197-1208. doi: 10.1007/s40273-024-01401-y. Epub 2024 Aug 7.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has increased public awareness of the influence of epidemiological and economic decision models on public policy decisions. Alongside this is an increased scrutiny on the development, analysis, reporting and utilisation of decision models for public policy making. Therefore, it is important that model developers can clearly explain and justify to all stakeholders what is included and excluded from a model developed to support decision-making, to both improve transparency and trust in decision-making. Our aim is to provide tools for improving communication between modellers and decision-makers, leading to improved transparency in decision-making. To do so, we extend the recently described directed acyclic graphs with omitted objects displayed (DAGWOOD) approach from Haber et al. (Ann Epidemiol 68:64-71, 2022) to decision analytic models, giving the decision analytic models with omitted objects displayed (DAMWOOD) approach. DAMWOOD is a framework for the identification of objects omitted from a decision model, as well as for consideration of the effects of omissions on model outcomes. Objects omitted from a decision model are classed as either an exclusion (known and unknown confounders), misdirection (alternative model pathways) or structure (e.g. model type, methods for estimating relationships between objects). DAMWOOD requires model developers to use explicit statements and provide illustration of included and omitted objects, supporting communication with model users and stakeholders, allowing them to provide input and feedback to modellers about which objects to include or omit in a model. In developing DAMWOOD, we considered two challenges we encountered in modelling for pandemic policy response. First, the scope of the decision problem is not always made sufficiently explicit by decision-makers, requiring modellers to intuit which policy options should be considered, and/or which outcomes should be considered in their evaluation. Second, there is rarely sufficient transparency to ensure stakeholders can see what is included in models and why. This limits stakeholders' ability to advocate to decision-makers for the prioritisation of specific outcomes and challenge the model results. To illustrate the application of DAMWOOD, we apply it to a previously published COVID-19 vaccine allocation optimisation model. The DAMWOOD diagrams illustrate the ways in which it is possible to improve the communication of model assumptions. The diagrams make explicit which outcomes are omitted and provide information on the expected impact of the omissions on model results. We discuss the usefulness of DAMWOOD for framing the decision problem, communicating the model structure and results and engaging with those making and affected by the decisions the model is developed to inform.

摘要

2019 年冠状病毒病(COVID-19)大流行提高了公众对流行病学和经济决策模型对公共政策决策影响的认识。与此同时,对用于公共政策制定的决策模型的开发、分析、报告和利用也进行了更严格的审查。因此,模型开发人员能够向所有利益相关者清楚地解释和说明从模型中排除和包含的内容,这一点非常重要,这有助于提高决策的透明度和信任度。我们的目标是提供工具,以改善建模者和决策者之间的沟通,从而提高决策的透明度。为此,我们扩展了 Haber 等人最近描述的带有省略对象的有向无环图(DAGWOOD)方法(Ann Epidemiol 68:64-71, 2022),以用于决策分析模型,从而得到带有省略对象的决策分析模型(DAMWOOD)方法。DAMWOOD 是一种用于识别从决策模型中省略的对象的框架,以及用于考虑省略对模型结果的影响的框架。从决策模型中省略的对象分为排除项(已知和未知的混杂因素)、误导项(替代模型途径)或结构(例如模型类型、用于估计对象之间关系的方法)。DAMWOOD 要求模型开发人员使用明确的语句并提供包含和省略对象的说明,这有助于与模型用户和利益相关者进行沟通,允许他们向建模人员提供有关在模型中包含或省略哪些对象的输入和反馈。在开发 DAMWOOD 时,我们考虑了在大流行政策应对建模中遇到的两个挑战。首先,决策者并未充分明确说明决策问题的范围,这要求建模人员凭直觉来确定应考虑哪些政策选项,以及/或者在评估中应考虑哪些结果。其次,很少有足够的透明度来确保利益相关者能够看到模型中包含的内容以及原因。这限制了利益相关者为决策者争取特定结果的优先级并对模型结果提出质疑的能力。为了说明 DAMWOOD 的应用,我们将其应用于之前发表的 COVID-19 疫苗分配优化模型。DAMWOOD 图说明了可以改善模型假设沟通的方式。这些图明确了省略了哪些结果,并提供了有关省略对模型结果影响的信息。我们讨论了 DAMWOOD 用于构建决策问题、沟通模型结构和结果以及与制定和受模型决策影响的人员进行互动的有用性。

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