Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), University of Heidelberg, Heidelberg, Germany.
Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), University of Heidelberg, Heidelberg, Germany.
Eur J Cancer. 2024 Sep;209:114255. doi: 10.1016/j.ejca.2024.114255. Epub 2024 Aug 2.
To reduce smoking uptake in adolescents, the medical students' network Education Against Tobacco (EAT) has developed a school-based intervention involving a face-aging mobile app (Smokerface).
A two-arm cluster-randomized controlled trial was conducted, evaluating the 2016 EAT intervention, which employed the mobile app Smokerface and which was delivered by medical students. Schools were randomized to intervention or control group. Surveys were conducted at baseline (pre-intervention) and at 9, 16, and 24 months post-intervention via paper & pencil questionnaires. The primary outcome was the difference in within-group changes in smoking prevalence between intervention and control group at 24 months.
Overall, 144 German secondary schools comprising 11,286 pupils participated in the baseline survey, of which 100 schools participated in the baseline and at least one of the follow-up surveys, yielding 7437 pupils in the analysis sample. After 24 months, smoking prevalence was numerically lower in the intervention group compared to control group (12.9 % vs. 14.3 %); however, between-group differences in change in smoking prevalence between baseline and 24-months follow-up (OR=0.83, 95 %-CI: 0.64-1.09) were not statistically significant (p = 0.176). Intention to start smoking among baseline non-smokers declined non-significantly in the intervention group (p = 0.064), and remained essentially unchanged in the control group, but between-group differences in changes at the 24-months follow-up (OR=0.88, 0.64-1.21) were not statistically significant (p = 0.417).
While a trend towards beneficial effects of the intervention regarding smoking prevalence as well as intention to start smoking among baseline non-smokers was observed, our smoking prevention trial demonstrated no significant effect of the intervention.
为了减少青少年的吸烟率，医学生网络教育反烟草（EAT）开发了一种基于学校的干预措施，包括一个面部老化的移动应用程序（Smokerface）。
进行了一项两臂整群随机对照试验，评估了 2016 年 EAT 干预措施，该干预措施使用了移动应用程序 Smokerface，并由医学生实施。学校被随机分为干预组或对照组。通过纸质问卷和铅笔问卷，在基线（干预前）以及干预后 9、16 和 24 个月进行调查。主要结局是 24 个月时干预组和对照组之间吸烟率的变化差异。
共有 144 所德国中学，共 11286 名学生参加了基线调查，其中 100 所学校参加了基线和至少一次随访调查，分析样本中共有 7437 名学生。24 个月后，干预组的吸烟率与对照组相比，数值上较低（12.9% vs. 14.3%）；然而，基线和 24 个月随访之间吸烟率变化的组间差异（OR=0.83，95%CI：0.64-1.09）无统计学意义（p=0.176）。基线时不吸烟的人中，开始吸烟的意向在干预组中略有下降（p=0.064），而在对照组中基本不变，但 24 个月随访时的组间差异（OR=0.88，0.64-1.21）无统计学意义（p=0.417）。
虽然观察到干预措施在吸烟率和基线不吸烟者开始吸烟的意向方面有朝着有益效果的趋势，但我们的吸烟预防试验显示干预措施没有显著效果。
