Das Siladitya, Laha Debal, Sengupta Prasenjit
Department of Neurology, Burdwan Medical College, West Bengal, India.
Ann Indian Acad Neurol. 2024 Jul 1;27(4):378-383. doi: 10.4103/aian.aian_44_24. Epub 2024 Aug 8.
Motor neuron diseases (MNDs) have been traditionally considered to spare cognition. But recent findings show that multiple domains of cognition including language can be involved in MND patients. Most studies on language patterns of MND patients were conducted in Western nations, but data on Indian population is limited. This study is an attempt to explore the language functions of Bengali-speaking MND patients from this part of eastern India.
To determine the prevalence and nature of language dysfunction in MND patients.
A single-center, hospital-based, observational, cross-sectional study. The Bengali adaptation of the Western Aphasia Battery was administered to 50 cases diagnosed with MND, attending a tertiary care hospital consecutively over a 1-year period, and fulfilling the inclusion and exclusion criteria for the study. Descriptive and inferential statistics were used for expressing results.
Eighteen percent of cases showed impairments in spontaneous speech. Fluency was impaired in 72%, and 22% cases showed impaired naming. Moreover, 20% and 26% of cases were impaired in repetition and comprehension, respectively. Reading and writing was impaired in 16% and 26% of cases, respectively. Significant difference was found in the primary language skill scores and aphasia quotient across age groups, while no significant difference was found in these scores across education status.
This study describes the language profiles of Bengali-speaking MND patients from eastern India, and the findings are similar to previous research works, which have shown morpho-syntactic, lexical-semantic, and phonological errors in language function.
运动神经元病（MNDs）传统上被认为不会影响认知。但最近的研究结果表明，包括语言在内的多个认知领域都可能在MND患者中出现问题。大多数关于MND患者语言模式的研究是在西方国家进行的，但关于印度人群的数据有限。本研究旨在探索印度东部这一地区说孟加拉语的MND患者的语言功能。
确定MND患者语言功能障碍的患病率和性质。
一项单中心、基于医院的观察性横断面研究。对50例被诊断为MND的患者进行了西方失语症成套测验的孟加拉语改编版测试，这些患者在1年的时间里连续就诊于一家三级护理医院，并符合该研究的纳入和排除标准。采用描述性和推断性统计来表达结果。
18%的病例表现出自发言语障碍。72%的病例流畅性受损，22%的病例命名受损。此外，分别有20%和26%的病例在复述和理解方面受损。阅读和书写受损的病例分别为16%和26%。不同年龄组的主要语言技能得分和失语商存在显著差异，而不同教育程度的这些得分没有显著差异。
本研究描述了印度东部说孟加拉语的MND患者的语言特征，研究结果与之前的研究相似，之前的研究表明语言功能存在形态句法、词汇语义和语音方面的错误。
