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皮肤学难题:认识嗜酸性粒细胞增多和全身症状的药物反应(DRESS)在有色人种患者皮肤中的皮肤表现的重要性。

A Dermatological Dilemma: The Importance of Recognizing Dermatologic Manifestations of Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS) in Skin of Color Patients.

作者信息

Qadir Nadim A, Marsalisi Christopher, Reddy Anvit D, Stachler Luke, Onteddu Nirmal

机构信息

Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

出版信息

Cureus. 2024 Jul 8;16(7):e64061. doi: 10.7759/cureus.64061. eCollection 2024 Jul.

Abstract

Many dermatologic conditions that are seen in medical literature are typically on lighter skin tones making it easier to identify. This can pose a difficult problem in the care of skin of color patients. The purpose of this paper is to highlight the importance of dermatologic manifestations in skin of color patients and the disparities that exist in the medical field. Here, we present the case of a 51-year-old African American male who was hospitalized on a prolonged course of antibiotics found to have drug reaction with eosinophilia and systemic symptoms (DRESS). Although the initial diagnosis was not made at symptom onset due to the atypical presentation in darker skin tones, the patient improved when the diagnosis was eventually made with cessation of the offending agent and steroid therapy. There is a vital need for continued awareness of the disparities that exist within medical literature and the medical field in regard to skin of color patients.

摘要

医学文献中记载的许多皮肤病通常在肤色较浅的人群中更易识别。这在有色人种患者的皮肤护理中可能会带来难题。本文旨在强调有色人种患者皮肤病表现的重要性以及医学领域中存在的差异。在此,我们呈现一例51岁非裔美国男性病例,该患者因长期使用抗生素住院,被发现患有药物超敏反应伴嗜酸性粒细胞增多和全身症状(DRESS)。尽管由于深色皮肤的非典型表现,在症状出现时未做出初始诊断,但在最终诊断并停用致病药物及进行类固醇治疗后,患者病情有所改善。迫切需要持续关注医学文献和医学领域中针对有色人种患者存在的差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76c4/11305447/ce239946e77f/cureus-0016-00000064061-i01.jpg

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