Liu Xiufeng, Lu Yinying, Zhou Weiping, Peng Tao, Zhou Jie, Bi Huaqiang, Xia Feng, Chen Xiaoping
Department of Medical Oncology of PLA Cancer Center, Jinling Hospital, Nanjing, China.
Comprehensive Liver Cancer Center, 5th Medical Center of PLA General Hospital, Beijing, China.
Liver Cancer. 2024 Jan 16;13(4):355-375. doi: 10.1159/000535496. eCollection 2024 Aug.
Immune checkpoint inhibitor (ICI)-based combination therapy modalities for hepatocellular carcinoma (HCC) have achieved significant efficacy in clinical research and practice and have become the mainstay for the treatment of unresectable HCC.
To better help clinicians use combination immunotherapy drugs and regimens rationally, effectively, and safely, the editorial board facilitated a discussion with multidisciplinary experts in the field, adopted the "Delphi" consensus formation method, and finally revised and completed the "" on the basis of the 2021 edition.
This consensus primarily focuses on the principles and methods of clinical practice of combination therapy based on ICIs, aiming to summarize the recommendations for clinical application based on the latest research and expert experience and provide application guidance for clinicians.
基于免疫检查点抑制剂(ICI)的肝细胞癌(HCC)联合治疗模式在临床研究和实践中已取得显著疗效,成为不可切除HCC治疗的主要手段。
为了更好地帮助临床医生合理、有效且安全地使用联合免疫治疗药物和方案,编辑委员会与该领域的多学科专家进行了讨论,采用“德尔菲”共识形成方法,并最终在2021年版的基础上修订完成了本《共识》。
本共识主要聚焦基于ICI的联合治疗临床实践的原则和方法,旨在根据最新研究和专家经验总结临床应用建议,为临床医生提供应用指导。