Thakur Sunil, Kanwar Manjit Singh, Sharma Anurag, Kaushal Sushruti, Marwaha Poojan Dogra, Sharma Nisha, Kumar Ravinder
Department of Anesthesia, AIIMS, Bilaspur, Himachal Pradesh, India.
Department of Anesthesia, Dr RK Govt Medical College, Hamirpur, Himachal Pradesh, India.
J Perianesth Nurs. 2025 Apr;40(2):326-330. doi: 10.1016/j.jopan.2024.05.007. Epub 2024 Aug 7.
Traditional prolonged fasting regimens have recently been replaced with guidelines to take carbohydrate-rich clear fluids until 2 hours before surgery. With this study, we wanted to study if the addition of carbohydrates to preoperative oral fluids confers any advantage.
Randomized clinical trial.
The study was conducted at a single center in North India among singleton pregnancies at term, scheduled for elective cesarean section under subarachnoid block. Participants were randomized into 2 groups of 50 participants each. The "Carbohydrate group" received 400 mL of fluid containing 50 g of glucose, while the "plain water" group received 400 mL of water 2 to 4 hours before surgery. A visual analog scale was used to assess hunger, thirst, anxiety, fatigue, and nausea before surgery. Intraoperative mean arterial pressure, hypotension, nausea, and vomiting were noted. On the first postoperative day, recovery from anesthesia was assessed using the Quality of recovery from anesthesia- 40 (QoR-40) questionnaire. Blood sugar levels were compared on the first postoperative day and in cord blood.
Preoperative visual analog scale scores for hunger, thirst, anxiety, nausea, and fatigue were similar in both groups. The occurrence of hypotension (P = .688) and phenylephrine use (P = .39), recovery from anesthesia (P = .92), cord blood sugar levels (P = .24), and postoperative blood sugar levels were also not significantly different in both groups (P = .81).
This study did not find any significant advantage of preoperative carbohydrate-containing fluid over preoperative plain water in women undergoing elective cesarean delivery under Subarachnoid block.
传统的长期禁食方案最近已被术前2小时饮用富含碳水化合物的清亮液体的指南所取代。通过本研究，我们想探究术前口服液体中添加碳水化合物是否具有任何优势。
随机临床试验。
该研究在印度北部的一个单一中心对足月单胎妊娠且计划在蛛网膜下腔阻滞下行择期剖宫产的孕妇进行。参与者被随机分为两组，每组50人。“碳水化合物组”在术前2至4小时饮用400毫升含50克葡萄糖的液体，而“清水组”饮用400毫升水。术前使用视觉模拟量表评估饥饿、口渴、焦虑、疲劳和恶心程度。记录术中平均动脉压、低血压、恶心和呕吐情况。术后第一天，使用麻醉恢复质量-40（QoR-40）问卷评估麻醉恢复情况。比较术后第一天和脐血中的血糖水平。
两组术前视觉模拟量表的饥饿、口渴、焦虑、恶心和疲劳评分相似。两组的低血压发生率（P = 0.688）、去氧肾上腺素使用情况（P = 0.39）、麻醉恢复情况（P = 0.92）、脐血血糖水平（P = 0.24）以及术后血糖水平也无显著差异（P = 0.81）。
本研究未发现蛛网膜下腔阻滞下行择期剖宫产术的女性术前饮用含碳水化合物的液体比术前饮用清水有任何显著优势。
