Rettori V, Goijman S, Rozados R
Arch Androl. 1979;3(2):135-8. doi: 10.3109/01485017908985060.
The effect of Pimozide on serum and pituitary concentration of LH was studied in adult male intact rats. Also the release of LH under stimulation of exogenous LH-RH was measured. The treatment for 5 days with pimozide did not alter the serum LH levels, decreased the release of LH by exogenous LH-RH stimulation, and increased the pituitary LH concentration. These results would indicate that blocking the dopaminergic receptors alters pituitary LH release mechanism.
在成年雄性未阉割大鼠中研究了匹莫齐特对血清和垂体中促黄体生成素（LH）浓度的影响。还测定了在外源性促性腺激素释放激素（LH-RH）刺激下LH的释放。用匹莫齐特治疗5天未改变血清LH水平，降低了外源性LH-RH刺激引起的LH释放，并增加了垂体LH浓度。这些结果表明阻断多巴胺能受体会改变垂体LH释放机制。
