Smell & Taste Clinic, Department of Otorhinolaryngology, ''Technische Universität Dresden'', Dresden, Germany.
Smell & Taste Clinic, Department of Otorhinolaryngology, ''Technische Universität Dresden'', Dresden, Germany.
J Neurosci Methods. 2024 Oct;410:110244. doi: 10.1016/j.jneumeth.2024.110244. Epub 2024 Aug 6.
Assessment of taste and somatosensory perception in clinical practice lacks fast tests that are validated and reliable. Recently, a 12-item identification test for taste and oral trigeminal perception, and its shorter version, the Seven-iTT, was developed. The objectives of this study were to evaluate its test-retest reliability and establish normative data.
Two-hundred participants (120 women, 80 men) with a good sense of taste performed a whole-mouth identification test using 12 filter-paper strips impregnated with low and high concentrations of sweet, sour, salty, bitter, astringency, and spiciness. Fifty of them repeated the task, with a median interval of 122 days from the first visit. Test-retest reliability was determined using Spearman correlation and the Bland-Altman plot method.
There was a significant correlation in identification score between the first and the second session for both versions of the test (r ≥ 0.28; p ≤ 0.048). The Bland-Altman plot reflected a good congruence between the results of the two sessions. Additionally, frequencies of correct identification were consistent between sessions, with women outperforming men (p = 0.005). Hypogeusia was established at Seven-iTT score of 3 of less.
The identification test combines taste and somatosensory perception, thus creating a more detailed diagnosis tool. Scores were correlated with self-rated taste perception.
The present results confirmed the applicability of Seven-iTT for a reliable, fast evaluation of taste and somatosensory perception in the general population, that can be extended to clinical practice.
临床评估味觉和体感感知缺乏经过验证和可靠的快速测试。最近，开发了一种包含 12 项味觉和口腔三叉神经感知识别测试的测试及其更短的版本 Seven-iTT。本研究的目的是评估其重测信度并建立正常数据。
200 名味觉良好的参与者（120 名女性，80 名男性）使用 12 个浸渍有低浓度和高浓度甜味、酸味、咸味、苦味、涩味和辣味的滤纸条进行全口识别测试。其中 50 人在第一次就诊后中位数间隔 122 天重复该任务。使用 Spearman 相关和 Bland-Altman 图法确定重测信度。
两种版本的测试在第一次和第二次测试之间的识别得分都存在显著相关性（r≥0.28；p≤0.048）。Bland-Altman 图反映了两次测试结果之间的良好一致性。此外，两次测试之间的正确识别频率一致，女性的表现优于男性（p=0.005）。Seven-iTT 得分低于 3 表示味觉减退。
识别测试结合了味觉和体感感知，因此创建了更详细的诊断工具。得分与自我评估的味觉感知相关。
本研究结果证实了 Seven-iTT 在一般人群中可靠、快速评估味觉和体感感知的适用性，可扩展到临床实践。
