Department of Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, SG, Singapore.
Singapore Eye Research Institute, SG, Singapore.
Eye (Lond). 2024 Oct;38(15):2859-2873. doi: 10.1038/s41433-024-03183-1. Epub 2024 Aug 8.
Lacquer cracks, described as breaks in the Bruch's membrane, are unique lesions in the spectrum of fundus changes associated with pathological myopia. Lacquer cracks are generally believed to be relatively innocuous lesions by themselves; however, progression to other features of myopic macular degeneration, such as patchy chorioretinal atrophy and choroidal neovascularization, may result in irreversible visual impairment. With the rising prevalence of pathological myopia to epidemic proportions, particularly in the Asian countries, ophthalmologists expect to encounter lacquer cracks more frequently in clinical practice. Therefore, it is crucial for the ophthalmic community to be aware of lacquer cracks and to actively look for these lesions in myopic patients so that early detection and close monitoring can help prevent blinding complications. This article provides a comprehensive review on lacquer cracks in eyes with pathological myopia from a clinical perspective.
漆裂纹，描述为布鲁赫膜破裂，是与病理性近视相关的眼底改变谱中的独特病变。漆裂纹通常被认为是本身相对无害的病变；然而，进展为其他近视性黄斑变性特征，如斑片状脉络膜视网膜萎缩和脉络膜新生血管形成，可能导致不可逆转的视力损害。随着病理性近视的患病率上升到流行程度，特别是在亚洲国家，眼科医生预计在临床实践中会更频繁地遇到漆裂纹。因此，眼科界必须意识到漆裂纹，并积极在近视患者中寻找这些病变，以便早期发现和密切监测，以防止致盲并发症。本文从临床角度对病理性近视眼中的漆裂纹进行了全面综述。
