University of Alabama at Birmingham, Birmingham, AL, USA.
University of Pennsylvania, Philadelphia, PA, USA.
Adv Exp Med Biol. 2024;1448:3-7. doi: 10.1007/978-3-031-59815-9_1.
The coronavirus disease 2019 (COVID-19) pandemic emerged just months after the publication of the first ever textbook devoted to cytokine storm syndromes (CSSs). The severe disease caused by COVID-19 and the intersection between immune responses and their pathologies played out before the world in media reports, in scientific publications, and through the personal narratives of millions of people's experiences. An entirely new immune-mediated disease, multisystem inflammatory disease in children (MISC), was described. Cytokines played a role in all of these areas, bringing the idea of a cytokine storm squarely to the front and center of the public eye. At the same time, science continued to progress in the lab and in the clinic, thus illuminating our understanding of CSSs both old and new since the publication of the first edition of this book. It was clear that a new edition was needed to keep up with these changes.
2019 年冠状病毒病（COVID-19）大流行是在第一本专门论述细胞因子风暴综合征（CSSs）的教科书出版仅几个月后出现的。COVID-19 引起的严重疾病以及免疫反应及其病理之间的交集在媒体报道、科学出版物以及数百万人的个人经历中展现在世人面前。一种全新的免疫介导疾病，儿童多系统炎症性疾病（MISC）被描述出来。细胞因子在所有这些领域都发挥了作用，使细胞因子风暴的概念直接成为公众关注的焦点。与此同时，科学在实验室和临床中继续取得进展，从而阐明了自本书第一版出版以来对新旧 CSSs 的理解。显然，需要一版新的书籍来跟上这些变化。
