Riefkohl R, Pollack S, Georgiade G S
Ann Plast Surg. 1985 Aug;15(2):99-104. doi: 10.1097/00000637-198508000-00003.
During a 56-month period, 1,348 patients with either basal cell or squamous cell carcinoma of the skin underwent microscopically controlled excision (Mohs' fresh-tissue technique) by a dermatologic surgeon. Of these 1,348 patients, 394 required various types of wound reconstruction by a plastic surgeon. The average dimensions of these wounds were 5 X 3.5 cm, with a range of 1.5 to 20.0 cm in diameter. There were postoperative complications in 13.9% of the 394 patients. The recurrence rate in these 394 patients, to date, for basal cell carcinoma is 5.2% and for squamous cell carcinoma, 11.9%. The advantages of this treatment arrangement include maximum conservation of normal tissue with provision of more reliable complete tumor excision, optimum time utilization by both dermatologic and plastic surgeons, separation of the responsibility for tumor ablation from that for wound reconstruction, and, in many instances, economic savings. We recommend this method of management for difficult, high-risk basal cell or squamous cell carcinomas.
在56个月的时间里，1348例患有基底细胞癌或皮肤鳞状细胞癌的患者接受了皮肤科医生进行的显微镜控制下切除（莫氏新鲜组织技术）。在这1348例患者中，394例需要整形外科医生进行各种类型的伤口重建。这些伤口的平均尺寸为5×3.5厘米，直径范围为1.5至20.0厘米。394例患者中有13.9%出现术后并发症。迄今为止，这394例患者中基底细胞癌的复发率为5.2%，鳞状细胞癌的复发率为11.9%。这种治疗安排的优点包括最大限度地保留正常组织，更可靠地完全切除肿瘤，皮肤科医生和整形外科医生能最佳地利用时间，将肿瘤切除的责任与伤口重建的责任分开，并且在许多情况下节省费用。对于困难的、高风险的基底细胞癌或鳞状细胞癌，我们推荐这种治疗方法。
