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术中使用吲哚菁绿血管造影术辅助诊断和治疗不明原因的消化道出血:一例报告

Intraoperative angiography with indocyanine green, an aid in the diagnosis and treatment of obscure digestive tract bleeding, a case report.

作者信息

Alquicira Alcantara Edson, de la Hoz Camacho Daniela, Pinedo Vega Angel D, Yescas Vázquez Xanat, Hernandez Bernal Pedro A, Medina Caballero Daniel

机构信息

General Surgery Department of the General Hospital "Eduardo Vazquez N", Antiguo Camino a Guadalupe Hidalgo 11350, Agua Santa, Puebla 72490, Mexico.

出版信息

Oxf Med Case Reports. 2024 Aug 6;2024(8):omae084. doi: 10.1093/omcr/omae084. eCollection 2024 Aug.

DOI:10.1093/omcr/omae084
PMID:39119014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11304940/
Abstract

Lower digestive tract bleeding occurs distal to the angle of Treitz. While many cases remit spontaneously; some pose a diagnostic challenge for surgeons. We present the case of a 68-year-old man with unexplained digestive tract bleeding. Despite various diagnostic efforts, the source remained unknown. Faced with the challenge of persistent bleeding and hemodynamic instability, surgery became necessary. During the procedure, intraoperative angiography with indocyanine green was used to facilitate the identification of the bleeding site, revealing a gastrointestinal stromal tumor in the small bowel. Resection was performed with favorable outcomes. Indocyanine green staining has become popular for locating intestinal bleeding during emergency surgeries, aiding surgeons in making precise decisions.

摘要

下消化道出血发生在屈氏韧带以下。虽然许多病例可自行缓解,但有些病例对外科医生来说是诊断难题。我们报告一例68岁不明原因消化道出血的男性病例。尽管进行了各种诊断努力,出血源仍不清楚。面对持续出血和血流动力学不稳定的挑战,手术成为必要。手术过程中,使用吲哚菁绿术中血管造影来协助确定出血部位,发现小肠有胃肠道间质瘤。进行了切除手术,效果良好。吲哚菁绿染色在急诊手术中定位肠道出血方面已很常用,有助于外科医生做出精确决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/8f2419e87525/omae084f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/60159553de72/omae084f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/986fa9fce4d3/omae084f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/8f2419e87525/omae084f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/60159553de72/omae084f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/986fa9fce4d3/omae084f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e85c/11304940/8f2419e87525/omae084f3.jpg

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本文引用的文献

1
Usefulness of indocyanine green fluorescence-guided small intestinal bleeding site identification in small bowel resection: a report of two cases and literature review.吲哚菁绿荧光引导下小肠出血部位识别在小肠切除术中的应用:两例报告及文献复习。
Clin J Gastroenterol. 2023 Jun;16(3):349-354. doi: 10.1007/s12328-023-01787-w. Epub 2023 Apr 12.
2
How to manage lower gastrointestinal bleeding in 2022?2022 年如何治疗下消化道出血?
J Visc Surg. 2022 Dec;159(6):486-496. doi: 10.1016/j.jviscsurg.2022.08.005. Epub 2022 Nov 12.
3
Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.
急性下消化道出血的诊断与管理:欧洲胃肠内镜学会(ESGE)指南
Endoscopy. 2021 Aug;53(8):850-868. doi: 10.1055/a-1496-8969. Epub 2021 Jun 1.
4
A Novel Indocyanine Green Fluorescence-Guided Laparoscopic Technique to Map the Site of Obscure Gastrointestinal Haemorrhage.一种新型吲哚菁绿荧光引导腹腔镜技术用于定位不明原因胃肠道出血部位。
Chirurgia (Bucur). 2021 Jan-Feb;116(1):89-101. doi: 10.21614/chirurgia.116.1.89.
5
Intraoperative angiography with indocyanine green injection for precise localization and resection of small bowel bleeding.术中注射吲哚菁绿进行血管造影以精确定位和切除小肠出血部位。
Acute Med Surg. 2020 Aug 13;7(1):e549. doi: 10.1002/ams2.549. eCollection 2020 Jan-Dec.
6
Acute Lower Gastrointestinal Bleeding: Evaluation and Management.急性下消化道出血:评估与管理。
Am Fam Physician. 2020 Feb 15;101(4):206-212.
7
Diagnosis and management of acute lower gastrointestinal bleeding: guidelines from the British Society of Gastroenterology.急性下消化道出血的诊断和治疗:英国胃肠病学会指南。
Gut. 2019 May;68(5):776-789. doi: 10.1136/gutjnl-2018-317807. Epub 2019 Feb 12.
8
Real-time fluorescence angiography by intra-arterial indocyanine green injection to identify obscure gastrointestinal bleeding territory: proof of concept in the porcine model.通过动脉内注射吲哚菁绿进行实时荧光血管造影以识别隐匿性胃肠道出血区域:猪模型中的概念验证
Surg Endosc. 2016 May;30(5):2143-50. doi: 10.1007/s00464-015-4460-y. Epub 2015 Aug 15.