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运动不足性肥厚型心肌病:新生儿自发性消退型的罕见病例。

Hypokinetic Hypertrophic Cardiomyopathy: A Rare Case of a Spontaneously Regressive Form in a Newborn.

作者信息

Lamouri Inasse, Ech-Chebab Mohammed, Ayyad Anass, Messaoudi Sahar, Babakhouya Abdeladim, Amrani Rim

机构信息

Department of Pediatrics, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Mohammed I University, Maternal-Child and Mental Health Research Laboratory, Oujda, MAR.

Department of Neonatology and Intensive Care Unit, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital, Mohammed I University, Oujda, MAR.

出版信息

Cureus. 2024 Jul 9;16(7):e64186. doi: 10.7759/cureus.64186. eCollection 2024 Jul.

Abstract

Hypertrophic cardiomyopathy (HCM) of the newborn is a rare condition, characterized by great clinical variability, with a relative paucity of data on the pediatric population, especially newborns. Early diagnosis can have an impact on the patient's life course and prevent progression to sudden death. In this article, we report the case of a newborn admitted with late-onset neonatal respiratory distress, complicated by heart failure. The newborn was matured by two antenatal injections of betamethasone, which were received as part of a threat of premature delivery. Echocardiography revealed hypokinetic HCM. The rapidity of the establishment of the diagnosis contributed to the patient's survival and improvement within a few weeks under well-managed medical treatment. A complete workup was conducted, with negative results. The most suggested explanation for this condition was the use of antenatal corticosteroids.

摘要

新生儿肥厚型心肌病(HCM)是一种罕见疾病,其临床变异性很大,关于儿科人群尤其是新生儿的数据相对较少。早期诊断可能会影响患者的生命历程并预防进展为猝死。在本文中,我们报告了一例因迟发性新生儿呼吸窘迫入院且并发心力衰竭的新生儿病例。该新生儿通过两次产前注射倍他米松促胎肺成熟,这是作为早产威胁的一部分进行的。超声心动图显示为运动减弱型HCM。诊断的确立速度有助于患者在精心管理的药物治疗下数周内存活并好转。进行了全面检查,结果均为阴性。对此病症最可能的解释是产前使用了皮质类固醇。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11309815/2dd4065e8b39/cureus-0016-00000064186-i01.jpg

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