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清醒镇静下静脉窦支架置入术。

Venous sinus stenting under conscious sedation.

作者信息

Kalsoum Erwah, Scarcia Luca, Abdalkader Mohamad, Dmytriw Adam A, Farhat Firas, Tuilier Titien, Geismar Maxime, Quesnel Christophe, Tourbah Ayman, Abdellaoui Mohamed, Nguyen Thanh N, Kikano Raghid, El Ojaimi Rami

机构信息

Department of Neuroradiology, Henri Mondor Hospital, Créteil, France.

Department of Neuroradiology, CHU Henri Mondor, Creteil, France.

出版信息

J Neurointerv Surg. 2025 Aug 13;17(9):939-942. doi: 10.1136/jnis-2024-022109.

DOI:10.1136/jnis-2024-022109
PMID:39122256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12421112/
Abstract

BACKGROUND

Venous sinus stenting (VSS) is an increasingly performed procedure for the treatment of idiopathic intracranial hypertension (IIH) refractory to medical treatment. VSS is typically performed under general anesthesia.

OBJECTIVE

To present our experience of VSS in patients with IIH performed under conscious sedation.

METHODS

Retrospective review of a prospectively maintained database of all patients with IIH who underwent VSS in a single center between September 2019 and January 2024. The sedation protocol consisted of a remifentanil-based target-controlled infusion. Patients' clinical and radiological data, dosage of anesthesia, procedural characteristics, and outcomes were collected.

RESULTS

Twenty-six patients with IIH underwent venous manometry (VM) and VSS under awake sedation and were included in our study. Patients were predominantly women (24/26) with a median age (IQR) of 33 (13) years. The median (IQR) body mass index was 34 (10) kg/m. There was no need for general anesthesia conversion. Technical success was achieved in all patients. Median (IQR) follow-up after stenting was 7 (2) months. All patients reported resolution of the pulsatile tinnitus; headaches regressed in 20/24 (83.3%) patients and papilledema improved in 16/20 (80%). Only one non-neurological complication (retroperitoneal hematoma) occurred, without any permanent morbidity or mortality.

CONCLUSION

Our study confirms that performing VM and VSS under conscious sedation is safe and feasible. Conscious sedation is a viable alternative to general anesthesia for managing IIH in these patients.

摘要

背景

静脉窦支架置入术(VSS)是治疗难治性特发性颅内高压(IIH)的一种应用日益广泛的手术。VSS通常在全身麻醉下进行。

目的

介绍我们在清醒镇静下对IIH患者进行VSS的经验。

方法

回顾性分析2019年9月至2024年1月在单一中心接受VSS的所有IIH患者的前瞻性维护数据库。镇静方案包括基于瑞芬太尼的靶控输注。收集患者的临床和影像学数据、麻醉剂量、手术特征及结果。

结果

26例IIH患者在清醒镇静下接受了静脉测压(VM)和VSS,并纳入我们的研究。患者以女性为主(24/26),中位年龄(四分位间距)为33(13)岁。中位(四分位间距)体重指数为34(10)kg/m²。无需转为全身麻醉。所有患者均取得技术成功。支架置入后的中位(四分位间距)随访时间为7(2)个月。所有患者均报告搏动性耳鸣消失;20/24(83.3%)的患者头痛减轻,16/20(80%)的患者视乳头水肿改善。仅发生1例非神经系统并发症(腹膜后血肿),无任何永久性发病或死亡。

结论

我们的研究证实,在清醒镇静下进行VM和VSS是安全可行的。清醒镇静是这些患者管理IIH时全身麻醉的一种可行替代方法。

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Neurosurgery. 2024 Apr 1;94(4):648-656. doi: 10.1227/neu.0000000000002718. Epub 2023 Oct 13.
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Cerebral venous disorders: Diagnosis and endovascular management.脑静脉疾病:诊断与血管内治疗。
J Neuroradiol. 2023 Nov;50(6):581-592. doi: 10.1016/j.neurad.2023.06.002. Epub 2023 Jun 16.
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A national survey of venous sinus stenting practices for idiopathic intracranial hypertension.一项针对特发性颅内高压患者静脉窦支架置入术实践的全国性调查。
J Neurointerv Surg. 2023 May;15(5):507-511. doi: 10.1136/neurintsurg-2022-018832. Epub 2022 Apr 15.
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Venous stenting for idiopathic intracranial hypertension: lessons learned from a high-volume practice.特发性颅内高压的静脉支架置入术:来自大量临床实践的经验教训
J Neurointerv Surg. 2022 Jun;14(6):528-532. doi: 10.1136/neurintsurg-2021-018184. Epub 2021 Sep 22.
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State of the Art: Venous Causes of Pulsatile Tinnitus and Diagnostic Considerations Guiding Endovascular Therapy.现状:静脉性搏动性耳鸣的病因及血管内治疗的诊断要点。
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[Preoperative risk and perioperative management of obese patients].肥胖患者的术前风险与围手术期管理
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Dural venous sinus stenting for idiopathic intracranial hypertension: An updated review.特发性颅内高压的硬脑膜静脉窦支架置入术:更新综述。
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Venous sinus stenting for idiopathic intracranial hypertension: a systematic review and meta-analysis.静脉窦支架置入术治疗特发性颅内高压:系统评价和荟萃分析。
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Recommendations for the selection and treatment of patients with idiopathic intracranial hypertension for venous sinus stenting.特发性颅内高压患者静脉窦支架置入术的选择和治疗建议。
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