Suppr超能文献

脑转移瘤治疗中的近距离放射治疗:技术进展与临床结果的范围综述

Brachytherapy in Brain Metastasis Treatment: A Scoping Review of Advances in Techniques and Clinical Outcomes.

作者信息

Leskinen Sandra, Ben-Shalom Netanel, Ellis Jason, Langer David, Boockvar John A, D'Amico Randy S, Wernicke A Gabriella

机构信息

Downstate Medical Center, State University of New York, New York, NY 11203, USA.

Department of Neurological Surgery, Zucker School of Medicine at Hofstra/Northwell, Lenox Hill Hospital, New York, NY 10075, USA.

出版信息

Cancers (Basel). 2024 Jul 31;16(15):2723. doi: 10.3390/cancers16152723.

Abstract

Brain metastases pose a significant therapeutic challenge in the field of oncology, necessitating treatments that effectively control disease progression while preserving neurological and cognitive functions. Among various interventions, brachytherapy, which involves the direct placement of radioactive sources into or near tumors or into the resected cavity, can play an important role in treatment. Current literature describes brachytherapy's capacity to deliver targeted, high-dose radiation while minimizing damage to adjacent healthy tissues-a crucial consideration in the choice of treatment modality. Furthermore, advancements in implantation techniques as well as in the development of different isotopes have expanded its efficacy and safety profile. This review delineates the contemporary applications of brachytherapy in managing brain metastases, examining its advantages, constraints, and associated clinical outcomes, and provides a comprehensive understanding of advances in the use of brachytherapy for brain metastasis treatment, with implications for improved patient outcomes and enhanced quality of life.

摘要

脑转移瘤在肿瘤学领域构成了重大的治疗挑战,需要有效的治疗方法来控制疾病进展,同时保留神经和认知功能。在各种干预措施中,近距离放射治疗,即将放射源直接放置在肿瘤内或肿瘤附近或切除腔内,在治疗中可发挥重要作用。当前文献描述了近距离放射治疗能够提供靶向、高剂量辐射,同时将对相邻健康组织的损害降至最低——这是选择治疗方式时的关键考虑因素。此外,植入技术以及不同同位素的开发进展扩大了其疗效和安全性。本综述阐述了近距离放射治疗在管理脑转移瘤方面的当代应用,研究了其优势、局限性和相关临床结果,并全面了解了近距离放射治疗在脑转移瘤治疗中的应用进展,对改善患者预后和提高生活质量具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9908/11311698/1f20ab04f94e/cancers-16-02723-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验