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WRKY转录因子的翻译后修饰

Post-Translational Modification of WRKY Transcription Factors.

作者信息

Zhou Xiangui, Lei Zaojuan, An Pengtian

机构信息

State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences and School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.

Huanghua Port Business Department, Technical Center of Shijiazhuang Customs District, Cangzhou 061113, China.

出版信息

Plants (Basel). 2024 Jul 25;13(15):2040. doi: 10.3390/plants13152040.

Abstract

Post-translational modifications (PTMs) of proteins are involved in numerous biological processes, including signal transduction, cell cycle regulation, growth and development, and stress responses. WRKY transcription factors (TFs) play significant roles in plant growth, development, and responses to both biotic and abiotic stresses, making them one of the largest and most vital TF families in plants. Recent studies have increasingly highlighted the importance of PTMs of WRKY TFs in various life processes. This review focuses on the recent advancements in understanding the phosphorylation and ubiquitination of WRKY TFs, particularly their roles in resistance to biotic and abiotic stresses and in plant growth and development. Future research directions and prospects in this field are also discussed.

摘要

蛋白质的翻译后修饰(PTMs)参与众多生物过程,包括信号转导、细胞周期调控、生长发育以及应激反应。WRKY转录因子(TFs)在植物生长、发育以及对生物和非生物胁迫的响应中发挥着重要作用,使其成为植物中最大且最重要的TF家族之一。最近的研究越来越强调WRKY TFs的翻译后修饰在各种生命过程中的重要性。本综述重点关注了在理解WRKY TFs的磷酸化和泛素化方面的最新进展,特别是它们在抵抗生物和非生物胁迫以及植物生长发育中的作用。还讨论了该领域未来的研究方向和前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/749c/11314200/b542418af307/plants-13-02040-g001.jpg

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