Department of Plant Breeding & Genetics, Ghazi University, D.G.Khan, Pakistan; College of Crop Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Departmentof Botany, Government College University, Faisalabad, Pakistan; College of Crop Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Microb Pathog. 2019 Oct;135:103610. doi: 10.1016/j.micpath.2019.103610. Epub 2019 Jul 6.
The WRKY transcription factors (TFs) family constitutes a major group of TFs in spermatophytes. Different studies have endorsed the considerable biological roles performed by WRKY TFs in plant growth, biotic and abiotic stress responses. Genomic and transcriptomic profiling facilitate us in understanding the WRKY genes in various plants and reveal how WRKY TFs perform their action in response to different plant stresses. WRKY TFs actively take part in metabolism including carbohydrate synthesis, senescence, and secondary metabolites production. Molecular organization of WRKY TFs in plants highlight most predicted outcome of multiple responses simultaneously. Repression and activation related to W-box and other such elements is controlled at transcriptional, translational and domain level. WRKY TFs are becoming more important in crop improvement because of their binding with downstream elements. Additionally, WRKY proteins intermingle with various other TFs for modulating plant immunity. However, WRKY TFs self-regulation and crosstalk between different signaling pathways using WRKY TFs still need extensive investigations. In this review, we focused characteristics of WRKY TFs in Capsicum annum and related research advancement on their functional involvement in plant responses to the challenges of high temperature stress and pathogens infection. We summarized information about Capsicum annum WRKY TFs on the basis of their functions, their target genes and signaling pathways. Moreover, the mechanisms for synergistic responses to various biotic and abiotic stresses, WRKY target genes and other TFs as well will be of more interest with increments in existing information.
WRKY 转录因子（TFs）家族构成了有性植物中 TF 的主要群体。不同的研究证实，WRKY TFs 在植物生长、生物和非生物胁迫反应中发挥着重要的生物学作用。基因组和转录组分析有助于我们了解各种植物中的 WRKY 基因，并揭示 WRKY TFs 如何在响应不同植物胁迫时发挥作用。WRKY TFs 积极参与代谢，包括碳水化合物合成、衰老和次生代谢产物的产生。植物中 WRKY TFs 的分子组织突出了多个响应的大多数预测结果。WRKY 基因的抑制和激活与 W-box 和其他类似元件有关，这种调节发生在转录、翻译和结构域水平。由于 WRKY TFs 与下游元件的结合，WRKY TFs 在作物改良中变得越来越重要。此外，WRKY 蛋白与各种其他 TF 相互作用，以调节植物的免疫。然而，WRKY TFs 的自我调节和不同信号通路之间的串扰仍然需要广泛的研究。在这篇综述中，我们重点介绍了辣椒中 WRKY TFs 的特征，并对其在植物应对高温胁迫和病原体感染等挑战中的功能参与进行了相关研究进展的综述。我们根据辣椒 WRKY TFs 的功能、靶基因和信号通路对其进行了总结。此外，随着现有信息的增加，WRKY TFs 对各种生物和非生物胁迫的协同反应机制、WRKY 靶基因和其他 TF 也将更受关注。
