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Monoclonal antibodies to the cells of a regenerating limb.

作者信息

Kintner C R, Brockes J P

出版信息

J Embryol Exp Morphol. 1985 Oct;89:37-55.

PMID:3912459
Abstract

Monoclonal antibodies were raised against differentiated cells, and blastemal cells from regenerating limbs of adult newts (Notophthalmus viridescens) and screened for specific staining by immunocytochemistry. In addition to antibodies that identify muscle, Schwann cells and cartilage, two reagents were specific for subpopulations of blastemal cells. One of these latter antibodies, termed 22/18, has provided new evidence about the origin of blastemal cells from Schwann cells and myofibres, and also identifies blastemal cells whose division is persistently dependent on the nerve supply.

摘要

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Monoclonal antibodies to the cells of a regenerating limb.
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