Breden Sebastian, Beischl Simone, Hinterwimmer Florian, Consalvo Sarah, Lenze Ulrich, von Eisenhart-Rothe Rüdiger, Pohlig Florian, Knebel Carolin
Department of Orthopedics and Sports Orthopedics, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
J Clin Med. 2024 Jul 27;13(15):4405. doi: 10.3390/jcm13154405.
The diagnostic work-up of musculoskeletal tumors is a multifactorial process. During the early phase, differential diagnoses are made using basic radiological imaging. In this phase, part of the decision making is based on the patient's age, as well as the incidence and predilection sites of different entities. Unfortunately, this information is based on older and fragmented data. In this study, we retrospectively evaluated all soft-tissue and bone tumors around the knee in children treated at our tertiary center in the last 20 years, with the aim of verifying the data used today. In this retrospective study, the databank of our tertiary center was used to give an overview of treated tumors around the knee in children. We were able to include 224 children with bone and soft-tissue tumors around the knee. The cohort consisted of 184 bone tumors, of which 144 were benign and 40 malignant. The 40 soft-tissue tumors comprised 30 benign and 10 malignant masses. The most common lesions were osteochondromas (88) in the bone and tenosynovial giant-cell tumors (12) in the soft tissue. With this original work, we were able to verify and supplement earlier studies, as well as deepen our insight into these very rare diseases.
肌肉骨骼肿瘤的诊断检查是一个多因素过程。在早期阶段，使用基本的放射影像学进行鉴别诊断。在这个阶段，部分决策基于患者的年龄，以及不同实体的发病率和好发部位。不幸的是，这些信息基于陈旧且零散的数据。在本研究中，我们回顾性评估了过去20年在我们三级中心接受治疗的儿童膝关节周围所有软组织和骨肿瘤，目的是验证目前使用的数据。在这项回顾性研究中，我们利用三级中心的数据库概述了儿童膝关节周围接受治疗的肿瘤情况。我们纳入了224例膝关节周围有骨和软组织肿瘤的儿童。该队列包括184例骨肿瘤，其中144例为良性，40例为恶性。40例软组织肿瘤包括30例良性和10例恶性肿块。最常见的病变是骨中的骨软骨瘤（88例）和软组织中的腱鞘巨细胞瘤（12例）。通过这项原创性工作，我们能够验证和补充早期研究，以及加深我们对这些非常罕见疾病的认识。
