Ciulpan Adrian, Lacatușu Adrian, Pop Liviu Laurenţiu, Paul Corina, Lungeanu Diana, Iacob Daniela, Bernad Brenda-Cristiana, Lascu Ana, Maghet Edida, Arnautu Diana-Aurora, Bernad Elena Silvia
Doctoral School, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
IInd Pediatrics Clinic, "Pius Brinzeu" County Clinical Emergency Hospital, 300723 Timișoara, Romania.
Diagnostics (Basel). 2024 Aug 1;14(15):1659. doi: 10.3390/diagnostics14151659.
Congenital heart defects (CHDs) are among the most frequent congenital defects, and they significantly burden the healthcare system due to their high mortality rate and high cost of care for survivors. We aimed to highlight the incidence of CHDs in a tertiary center in Western Romania.
A retrospective study was carried out between 2018 and 2022 at the "Pius Brinzeu" Emergency County Hospital Timisoara. Relevant information about the mothers and the newborns were collected and statistically analyzed.
The incidence of CHDs from 2018 to 2022 in our center was 5.3%. Eleven types of malformations were diagnosed postnatally in 541 newborns, with 28.8% of cases having more than one type of CHD. The antenatal detection rate was 28%, with the highest rates for tetralogy of Fallot, hypoplastic left heart syndrome, or significant ventricular septal defects and the lowest for pulmonary stenosis. The lower antenatal detection rate was influenced mainly by incomplete or absent prenatal care.
The incidence of CHDs is clearly dependent of a multifactorial approach, and the results highlight this. With an incidence almost 50% lower than reported within the literature and a low rate of prenatal detections, CHDs could be a more of a burden to endure regarding medical treatment. Improvements in patients' education, prenatal care, and screening programs could improve diagnosis, decrease mortality, and optimize postnatal care.
先天性心脏病（CHD）是最常见的先天性缺陷之一，因其高死亡率和幸存者高昂的护理成本给医疗系统带来了沉重负担。我们旨在突出罗马尼亚西部一家三级中心的先天性心脏病发病率。
2018年至2022年在蒂米什瓦拉的“皮乌斯·布林泽乌”县急救医院进行了一项回顾性研究。收集了有关母亲和新生儿的相关信息并进行统计分析。
2018年至2022年我们中心先天性心脏病的发病率为5.3%。在541名新生儿中产后诊断出11种畸形类型，28.8%的病例患有不止一种先天性心脏病。产前检出率为28%，法洛四联症、左心发育不全综合征或大型室间隔缺损的检出率最高，肺动脉狭窄的检出率最低。较低的产前检出率主要受产前护理不完整或缺失的影响。
先天性心脏病的发病率显然取决于多因素方法，结果也突出了这一点。其发病率比文献报道的低近50%，产前检出率也低，在医疗方面，先天性心脏病可能是更需承受的负担。改善患者教育、产前护理和筛查项目可改善诊断、降低死亡率并优化产后护理。
