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2005 年至 2017 年期间儿童先天性心脏病(CHD)手术后住院死亡率的特征:单中心经验。

Characteristics of in-hospital mortality of congenital heart disease (CHD) after surgical treatment in children from 2005 to 2017: a single-center experience.

机构信息

Pediatric Intensive Care Unit, Department of Pediatrics, Guangdong Provincial People's Hospital (GDPH), Guangdong Academy of Medical Sciences, Guangzhou, China.

Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital (GDPH), Guangdong Academy of Medical Sciences, 106 zhongshan Er Road, Guangzhou, Guangdong, China.

出版信息

BMC Pediatr. 2021 Nov 23;21(1):521. doi: 10.1186/s12887-021-02935-2.

Abstract

BACKGROUND

To evaluate trends in the in-hospital mortality rate for pediatric cardiac surgery procedures between 2005 and 2017 in our center, and to discuss the mortality characteristics of children's CHD after thoracotomy.

METHODS

This retrospective data were collected from medical records of children underwent CHD surgery between 2005 and 2017.

RESULTS

A total of 19,114 children with CHD underwent surgery and 444 children died, with the in-hospital mortality was 2.3%. Complex mixed defect CHD had the highest fatality rate (8.63%), left obstructive lesion CHD had the second highest fatality rate (4.49%), right to left shunt CHD had the third highest mortality rate (3.51%), left to right shunt CHD had the lowest mortality rate (χ2 = 520.3,P < 0.05). The neonatal period has the highest mortality rate (12.17%), followed by infant mortality (2.58%), toddler age mortality (1.16%), and preschool age mortality (0.94%), the school age and adolescent mortality rate was the lowest (χ2 = 529.3,P < 0.05). In addition, the fatality rate in boys was significantly higher than that in girls (2.77% versus 1.62%, χ2 = 26.4, P < 0.05).

CONCLUSIONS

The mortality rate of CHD surgery in children decreased year by year. The younger the age and the more complicated the cyanotic heart disease, the higher the mortality rate may be.

摘要

背景

评估 2005 年至 2017 年期间本中心小儿心脏手术住院死亡率的趋势,并讨论剖胸后儿童 CHD 的死亡率特征。

方法

本回顾性数据来自 2005 年至 2017 年间接受 CHD 手术的儿童病历。

结果

共有 19114 例 CHD 患儿接受手术,444 例患儿死亡,院内死亡率为 2.3%。复杂混合性缺陷 CHD 的病死率最高(8.63%),左阻塞性病变 CHD 病死率次之(4.49%),右向左分流 CHD 病死率第三(3.51%),左向右分流 CHD 病死率最低(χ2=520.3,P<0.05)。新生儿期死亡率最高(12.17%),其次为婴儿期(2.58%),幼儿期(1.16%),学龄前(0.94%),学龄期和青春期死亡率最低(χ2=529.3,P<0.05)。此外,男孩的病死率明显高于女孩(2.77%比 1.62%,χ2=26.4,P<0.05)。

结论

儿童 CHD 手术的死亡率逐年下降。年龄越小,紫绀型心脏病越复杂,死亡率可能越高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c24/8609813/6c4037bb19e1/12887_2021_2935_Fig1_HTML.jpg

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