Costa Martins J E, Vasconcellos C, Dinato S L, Belliboni N, Sotto M N
Med Cutan Ibero Lat Am. 1985;13(4):301-11.
The authors studied two patients with bullous lesions with onset at adult age. There were no relatives with bullous disease. After minor traumas, mainly in hands, feet, elbows and knees, one could see the onset of the blisters, which vanished leaving atrophic scars. Nails and mucosae were involved in both patients. The female patient had cyst of milia. One of the patients had lymph node tuberculosis as associated disease. Through exhaustive clinical examination and laboratory investigation, the authors excluded other types of bullous diseases. Histopathology of the lesions, electron microscopy, direct and indirect immunofluorescence, supported the diagnosis of Acquired Dermolytic Bullous Dermatosis.
作者研究了两名成年起病的大疱性皮损患者。他们没有患大疱性疾病的亲属。在轻微创伤后,主要发生在手、脚、肘和膝部,会出现水疱,水疱消失后留下萎缩性瘢痕。两名患者的指甲和黏膜均受累。女性患者有粟丘疹囊肿。其中一名患者伴有淋巴结结核。通过详尽的临床检查和实验室检测,作者排除了其他类型的大疱性疾病。皮损的组织病理学、电子显微镜检查、直接和间接免疫荧光检查均支持获得性皮肤松解性大疱病的诊断。