Cuadra Oyanguren J, Barbera Montesinos E, Sánchez Carazo J L, Aliaga Boniche A
Med Cutan Ibero Lat Am. 1985;13(4):357-61.
During the summer months three young patients were examined by us for an asymptomatic cutaneous eruption of erythematous papules located on neck, shoulders and back. They were heat-resistant to several antiseptics and systemic antibiotic treatment. The mechanical expression of these lesions did not reveal the appearance of pus, but a hard keratinous matter. The histopathological findings of the lesions show a non specific folliculitis, but the PAS stain shows numerous spores of yeast forms within the keratinous material of the follicle. The culture of this material in bacteriological and mycological ordinary media is negative, but the culture in the Dixon media reveals the growth of typical colonies of Pityrosporum orbiculare. The patients responded successfully to a 3 weeks course of ketoconazole (200 mgr/d).
在夏季的几个月里，我们检查了三名年轻患者，他们颈部、肩部和背部出现了无症状的红斑丘疹性皮肤疹。这些皮疹对几种防腐剂和全身抗生素治疗均有抗药性。对这些皮损进行机械挤压时，并未挤出脓液，而是一种坚硬的角质物质。皮损的组织病理学检查结果显示为非特异性毛囊炎，但过碘酸雪夫（PAS）染色显示在毛囊角质物质内有大量酵母样孢子。将该物质接种于普通细菌学和真菌学培养基中培养为阴性，但在迪克森培养基中培养则显示出圆形糠秕孢子菌的典型菌落生长。患者接受了为期3周的酮康唑（200毫克/天）治疗，疗效显著。
