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微波法从南洋杉树胶合成荧光碳量子点:在药物检测中的应用

Microwave Synthesis of Fluorescent Carbon Quantum dots from Araucaria Heterophylla Gum: Application in Drug Detection.

作者信息

Kumar Rohitash, Bhardwaj Vimal K

机构信息

Department of Chemistry, Dr. B. R. Ambedkar National Institute of Technology, Jalandhar, Punjab, India.

出版信息

J Fluoresc. 2024 Aug 10. doi: 10.1007/s10895-024-03874-8.

Abstract

This study employed a green microwave synthesis technique to produce carbon quantum dots (CQDs) from araucaria heterophylla gum extract. The produced CQDs emit a distinct blue fluorescent light, contributing a remarkable quantum yield of 14.69%. Their average particle size measures at 1.62 ± 0.39 nm. Furthermore, these CQDs demonstrate excellent water solubility and maintain high fluorescence stability despite ionic strength, pH and time variations. Moreover, we present here for the first time that the synthesized CQDs demonstrate a rapid, exceptionally sensitive, and discerning fluorescence quenching phenomenon (IFE) concerning Cefprozil (CPR). The fluorescent probe was sensitive and specific with good linear relationships for CPR in the 0-18 µM range. The limit of detection for relationships for CPR was 2.51 µM. This study provides novel opportunities for producing high-quality luminescent CQDs that meet the requirements for various biological and environmental applications.

摘要

本研究采用绿色微波合成技术,从南洋杉树胶提取物中制备碳量子点(CQDs)。所制备的CQDs发出独特的蓝色荧光,量子产率高达14.69%。其平均粒径为1.62±0.39纳米。此外,这些CQDs表现出优异的水溶性,并且在离子强度、pH值和时间变化的情况下仍保持高荧光稳定性。此外,我们首次在此展示了合成的CQDs对头孢丙烯(CPR)表现出快速、极其灵敏且具有识别性的荧光猝灭现象(IFE)。该荧光探针在0至18μM范围内对CPR敏感且具有特异性,线性关系良好。CPR的检测限为2.51μM。本研究为生产满足各种生物和环境应用要求的高质量发光CQDs提供了新的机遇。

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