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[晚期卵巢癌的二线化疗——新药]

[Secondary chemotherapy in advanced ovarian cancer--new drugs].

作者信息

Bruntsch U

出版信息

Onkologie. 1985 Dec;8(6):410-6. doi: 10.1159/000215698.

Abstract

The results of secondary chemotherapy in advanced ovarian carcinoma are reviewed. After treatment with alkylants average rates of remission of 40 to 45% are achieved. The duration of remission is about 5 months. The response after treatment with platin is significantly lower. Furthermore, new drugs are summarized. A new class of agents is not identifiable. Advances are to be expected in platin derivates with lower nephrotoxicity rates.

摘要

对晚期卵巢癌二线化疗的结果进行了综述。使用烷化剂治疗后,平均缓解率达到40%至45%。缓解期约为5个月。铂类药物治疗后的反应明显较低。此外,还总结了新药。尚未发现新的药物类别。预计肾毒性较低的铂衍生物会取得进展。

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