Bruntsch U
Onkologie. 1985 Dec;8(6):410-6. doi: 10.1159/000215698.
The results of secondary chemotherapy in advanced ovarian carcinoma are reviewed. After treatment with alkylants average rates of remission of 40 to 45% are achieved. The duration of remission is about 5 months. The response after treatment with platin is significantly lower. Furthermore, new drugs are summarized. A new class of agents is not identifiable. Advances are to be expected in platin derivates with lower nephrotoxicity rates.
对晚期卵巢癌二线化疗的结果进行了综述。使用烷化剂治疗后,平均缓解率达到40%至45%。缓解期约为5个月。铂类药物治疗后的反应明显较低。此外,还总结了新药。尚未发现新的药物类别。预计肾毒性较低的铂衍生物会取得进展。