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基于 CT 肠造影术预测克罗恩病的肛周瘘管

Prediction of Perianal Fistula in Crohn's Disease by Computed Tomography Enterography.

机构信息

Department of Radiology, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China.

Department of Inflammatory Bowel Disease Center, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China.

出版信息

Turk J Gastroenterol. 2024 Mar;35(3):168-177. doi: 10.5152/tjg.2024.22850.

DOI:10.5152/tjg.2024.22850
PMID:39128117
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11059798/
Abstract

BACKGROUND/AIMS: The purpose of this study was to investigate whether computed tomography enterography can be used to predict the presence of perianal fistula in Crohn's disease patients.

MATERIALS AND METHODS

According to the presentation of perianal fistula or not, this study divided retrospectively included Crohn's disease patients into 2 groups. The disease duration, incidence of involved intestinal segments, and scoring of the activity of the lesions in all patients were statistically analyzed to explore significant factors between the 2 groups. The statistically significant findings identified in the univariate analysis were incorporated into the multivariate analysis. Logistic regression models were subsequently constructed to assess the predictive factors associated with the occurrence of perianal fistula in individuals with Crohn's disease.The contribution of each factor to the outcome variable was confirmed by the nomogram. The clinical utility of the nomogram was confirmed by calibration and decision curves.

RESULTS

There were 40 cases with perianal Crohn's disease and 58 without perianal Crohn's disease. After univariate and multivariate analysis, disease duration (early stage of Crohn's disease), ascending colon, and rectum were identified as the independent predictive factors for perianal fistula in Crohn's disease patients. The clinical utility of the nomogram was effective, which implied potential benefits for Crohn's disease patients.

CONCLUSION

Computed tomography enterography can be used to predict the presence of perianal fistula in Crohn's disease patients by analyzing the location and the stage of the disease.

摘要

背景/目的：本研究旨在探讨 CT 肠造影是否可用于预测克罗恩病患者是否存在肛周瘘。

材料和方法

根据是否存在肛周瘘，本研究回顾性地将克罗恩病患者分为两组。对所有患者的疾病持续时间、受累肠段的发生率和病变活动评分进行统计分析，以探讨两组间的显著因素。单因素分析中发现的有统计学意义的发现被纳入多因素分析。随后构建了逻辑回归模型，以评估与克罗恩病患者发生肛周瘘相关的预测因素。通过列线图确认每个因素对结果变量的贡献。通过校准和决策曲线确认列线图的临床实用性。

结果

有 40 例存在肛周克罗恩病，58 例无肛周克罗恩病。经过单因素和多因素分析，疾病持续时间（克罗恩病早期）、升结肠和直肠被确定为克罗恩病患者发生肛周瘘的独立预测因素。列线图的临床实用性有效，这意味着对克罗恩病患者有潜在的获益。

结论

通过分析疾病的位置和阶段，CT 肠造影可用于预测克罗恩病患者是否存在肛周瘘。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/b0285583ddce/tjg-35-3-168_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/e7b2ec7c655a/tjg-35-3-168_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/bbe8768e07f7/tjg-35-3-168_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/4a38d9dace42/tjg-35-3-168_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/4053a9567dff/tjg-35-3-168_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/b0285583ddce/tjg-35-3-168_f005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/e7b2ec7c655a/tjg-35-3-168_f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/bbe8768e07f7/tjg-35-3-168_f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/4a38d9dace42/tjg-35-3-168_f003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/4053a9567dff/tjg-35-3-168_f004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b7a/11059798/b0285583ddce/tjg-35-3-168_f005.jpg

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本文引用的文献

1
Perianal disease onset age is associated with distinct disease features and need for intestinal resection in perianal Crohn's disease: a ten-year hospital-based observational study in China.肛周疾病发病年龄与肛周克罗恩病的不同疾病特征和需要肠道切除术有关：中国一项基于医院的十年观察性研究。
BMC Gastroenterol. 2021 Oct 14;21(1):376. doi: 10.1186/s12876-021-01961-9.
2
Perianal Crohn's disease: clinical implications, prognosis and use of resources.肛周克罗恩病：临床意义、预后和资源利用。
Rev Esp Enferm Dig. 2022 May;114(5):254-258. doi: 10.17235/reed.2021.7918/2021.
3
Clinical outcomes and long-term prognosis of perianal Crohn's disease in an Asian population.
亚洲人群肛周克罗恩病的临床结局及长期预后
J Gastroenterol Hepatol. 2021 Jun;36(6):1571-1579. doi: 10.1111/jgh.15308. Epub 2020 Nov 15.
4
Perianal Crohn's Disease.肛周克罗恩病。
Dis Colon Rectum. 2020 Aug;63(8):1023-1026. doi: 10.1097/DCR.0000000000001748.
5
Crohn's disease.克罗恩病。
Nat Rev Dis Primers. 2020 Apr 2;6(1):22. doi: 10.1038/s41572-020-0156-2.
6
Magnetic resonance imaging findings in patients with initial manifestations of perianal fistulas.磁共振成像在肛周瘘初始表现患者中的应用。
Ann Saudi Med. 2020 Jan-Feb;40(1):42-48. doi: 10.5144/0256-4947.2020.42. Epub 2020 Feb 6.
7
Small Bowel Crohn Disease at CT and MR Enterography: Imaging Atlas and Glossary of Terms.小肠克罗恩病的 CT 和 MR 肠造影表现：成像图谱与术语汇编。
Radiographics. 2020 Mar-Apr;40(2):354-375. doi: 10.1148/rg.2020190091. Epub 2020 Jan 17.
8
Advances in Perianal Disease Associated with Crohn's Disease-Evolving Approaches.克罗恩病相关肛周疾病的进展——不断演变的治疗方法
Gastrointest Endosc Clin N Am. 2019 Jul;29(3):515-530. doi: 10.1016/j.giec.2019.02.011.
9
MRI reveals different Crohn's disease phenotypes in children and adults.MRI 揭示了儿童和成人克罗恩病的不同表型。
Eur Radiol. 2019 Sep;29(9):5082-5092. doi: 10.1007/s00330-019-6006-5. Epub 2019 Feb 7.
10
Deep remission on magnetic resonance imaging impacts outcomes of perianal fistulizing Crohn's disease.磁共振成像深度缓解可影响肛周瘘管型克罗恩病的结局。
Dig Liver Dis. 2019 Mar;51(3):358-363. doi: 10.1016/j.dld.2018.12.010. Epub 2018 Dec 23.