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评估 STANDARD™ M10 从支气管肺泡灌洗样本中检测 SARS-CoV-2 的效果。

Evaluation of STANDARD™ M10 SARS-CoV-2 from bronchoalveolar lavage samples.

机构信息

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy.

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

出版信息

Diagn Microbiol Infect Dis. 2024 Nov;110(3):116466. doi: 10.1016/j.diagmicrobio.2024.116466. Epub 2024 Jul 31.

Abstract

Detection of SARS-CoV-2 in bronchoalveolar lavage (BAL) is considered as a promising alternative method to detect COVID-19 infection. STANDARD™ M10 SARS-CoV-2 assay on 150 negative and 50 positives BAL samples for SARS-CoV-2 showed 96 % sensitivity, 100 % specificity compared to Allplex™ SARS-CoV-2 assay and a 31.25 genomic copies/mL limit of detection.

摘要

检测支气管肺泡灌洗液 (BAL) 中的 SARS-CoV-2 被认为是一种很有前途的替代方法,可用于检测 COVID-19 感染。STANDARD™ M10 SARS-CoV-2 检测试剂盒在 150 份阴性 BAL 样本和 50 份阳性 BAL 样本中,与 Allplex™ SARS-CoV-2 检测试剂盒相比,其灵敏度为 96%,特异性为 100%,检测限为 31.25 基因组拷贝/mL。

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