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鱼类中有机化学品的水溶性、正辛醇/水分配系数与生物富集之间的关系:综述

Relation between water solubility, octanol/water partition coefficients, and bioconcentration of organic chemicals in fish: a review.

作者信息

van Gestel C A, Otermann K, Canton J H

出版信息

Regul Toxicol Pharmacol. 1985 Dec;5(4):422-31. doi: 10.1016/0273-2300(85)90007-8.

DOI:10.1016/0273-2300(85)90007-8
PMID:3912852
Abstract

A survey was made of the literature describing relations between water solubility (S), the octanol-water partition coefficient (Poct), and the bioconcentration factor (BCF) of organic chemicals. Based on the relations between BCF and Poct it can be concluded that mostly BCF is log BCF = 0.79 log Poct-0.40. From relations between Poct and S it can be concluded that for most organic chemicals log Poct will not exceed 3 if S is greater than ca. 3 mmol/liter. This limit is far more reliable than the value of 2000 mg/liter which has been proposed by OECD Experts and confirmed by other authors.

摘要

对描述有机化学品的水溶性(S)、正辛醇-水分配系数(Poct)和生物浓缩因子(BCF)之间关系的文献进行了调查。根据BCF与Poct之间的关系,可以得出结论,大多数情况下BCF为log BCF = 0.79 log Poct - 0.40。从Poct与S之间的关系可以得出结论,对于大多数有机化学品,如果S大于约3 mmol/升,则log Poct不会超过3。这个限值比经合组织专家提出并得到其他作者证实的2000 mg/升的值可靠得多。

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Regul Toxicol Pharmacol. 1985 Dec;5(4):422-31. doi: 10.1016/0273-2300(85)90007-8.
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