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微创,高效:精准细胞分析在胸水中的威力——从传统方法到创新方法的全面探索。

Minimally Invasive, Maximally Effective: The Power of Precision Cytoanalysis on Effusion Samples-A Comprehensive Exploration from Traditional Methods to Innovative Approaches.

机构信息

IPATIMUP Diagnostics, IPATIMUP-Institute of Molecular Pathology and Immunology of Porto University, Porto, 4200-135, Portugal.

IPATIMUP Diagnostics, IPATIMUP-Institute of Molecular Pathology and Immunology of Porto University, Porto, 4200-135, Portugal; Faculty of Medicine of the University of Porto, Porto, 4200-319, Portugal; CINTESIS@RISE (Health Research Network), Porto, 4200-319, Portugal.

出版信息

Surg Pathol Clin. 2024 Sep;17(3):453-481. doi: 10.1016/j.path.2024.04.008. Epub 2024 Jul 14.

Abstract

Precision medicine translates through molecular assays and in minimally invasive diagnosis, evident in analyses of effusions that serve therapeutic and diagnostic purposes. This cost-effective and low-risk approach provides advantages, playing a pivotal role in late-stage oncology and frequently standing as the primary resource for cancer diagnosis and treatment pathways. This article outlines the workflow for managing serous fluid and explores how cytology effusion analysis extends beyond immunocytological diagnosis. Combined with current molecular tests it showcases the potential to be a skillful tool in precision cytopathology.

摘要

精准医学通过分子检测和微创诊断来实现,这在分析用于治疗和诊断目的的渗出液时尤为明显。这种具有成本效益和低风险的方法具有优势,在肿瘤晚期治疗中发挥着关键作用,并且通常是癌症诊断和治疗途径的主要资源。本文概述了管理浆膜液的工作流程,并探讨了细胞病理学分析如何超越免疫细胞诊断。结合当前的分子检测,它展示了在精准细胞病理学中成为一种熟练工具的潜力。

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