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草药洞察:探索印度食用草药在糖尿病性心肌病管理中的治疗潜力。

Herbal Insights: Exploring the Therapeutic Potential of Indian Dietary Herbs in Diabetic Cardiomyopathy Management.

作者信息

Kaur Prabhnain, Vishwakarma Vishal Kumar, Singh Aditya, Goyal Ramesh K

机构信息

Delhi Institute of Pharmaceutical Sciences and Research Department of Pharmacy, School of Medical and Allied Sciences New Delhi India.

Delhi Institute of Pharmaceutical Sciences and Research Department of Pharmacology New Delhi India.

出版信息

Curr Diabetes Rev. 2024 Aug 9. doi: 10.2174/0115733998315714240801193254.

Abstract

BACKGROUND

Diabetic Cardiomyopathy (DCM) poses a substantial healthcare challenge, necessitating innovative therapeutic strategies. This review delves into the evolving role of traditional Indian dietary herbs in managing DCM, aiming to shed light on their potential contributions.

METHODS

A comprehensive examination of the existing body of literature was conducted, synthesizing data from studies exploring the effects of various Indian dietary herbs on DCM. Molecular mechanisms, clinical outcomes, and safety profiles were scrutinized to establish a holistic perspective on their therapeutic potential.

RESULTS

The review illuminates the multifaceted benefits of Indian dietary herbs in DCM management. These herbs have demonstrated efficacy in mitigating cardiac dysfunction, reducing oxidative stress, and modulating inflammatory responses. Molecular insights highlight their role in the intricate signaling pathways underlying DCM. Furthermore, their safety profiles render them promising candidates for adjunct therapy.

CONCLUSION

Indian dietary herbs emerge as promising allies in the battle against DCM, offering a holistic approach to the management of this intricate condition. Their cardioprotective effects, coupled with their ability to address the underlying molecular mechanisms, herald a new era in DCM therapy. This review underscores the need for further research to harness the potential of these herbs fully and provides a beacon of hope for individuals affected by DCM.

摘要

背景

糖尿病性心肌病(DCM)对医疗保健构成了重大挑战,需要创新的治疗策略。本综述深入探讨了传统印度药草在管理DCM方面不断演变的作用,旨在阐明它们的潜在贡献。

方法

对现有文献进行了全面审查,综合了探索各种印度药草对DCM影响的研究数据。对分子机制、临床结果和安全性进行了仔细审查,以建立对其治疗潜力的整体认识。

结果

该综述揭示了印度药草在DCM管理中的多方面益处。这些药草已证明在减轻心脏功能障碍、降低氧化应激和调节炎症反应方面具有功效。分子层面的见解突出了它们在DCM潜在复杂信号通路中的作用。此外,它们的安全性使其成为辅助治疗的有前景的候选药物。

结论

印度药草在对抗DCM的斗争中成为有前景的盟友,为管理这种复杂病症提供了一种整体方法。它们的心脏保护作用,以及解决潜在分子机制的能力,预示着DCM治疗的新时代。本综述强调需要进一步研究以充分利用这些药草的潜力,并为受DCM影响的个体提供了希望之光。

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