College of Chemistry and Chemical Engineering, Guangxi University, Nanning, China.
College of Food and Light Industry, Guangxi University, Nanning, China.
Luminescence. 2024 Aug;39(8):e4858. doi: 10.1002/bio.4858.
The research outlined a novel approach for creating a sensitive and efficient ratio fluorescent probe for ciprofloxacin (CIP) detection. The method used the biomass materials passionfruit shell and diethylenetriamine as carbon and nitrogen sources, respectively, to prepare blue fluorescent carbon quantum dots (b-CQDs) with an average size of 3.29 nm and a quantum yield of 19.6% by a hydrothermal method. The newly designed b-CQDs/riboflavin ratio fluorescent probe demonstrates a distinct advantage for CIP monitoring, exhibiting a marked increase in fluorescence intensity at 445 nm upon interaction with CIP, while maintaining a stable intensity at 510 nm. In the water system, the I/I ratio of the fluorescent probe showed a significant linear relationship with CIP at the concentrations of 0-250 μmol·L, and the probe boasts a low detection limit of 0.86 μmol·L. The outstanding selectivity, broad detection range, low detection limits, and high quantum yield of the b-CQDs highlight their significant potential in the development of advanced sensing probes for efficient detection of ciprofloxacin, offering promising insights for future sensor technology advancements.
该研究提出了一种新颖的方法，用于创建一种用于环丙沙星（CIP）检测的灵敏且高效的比率荧光探针。该方法使用生物质材料西番莲壳和二乙烯三胺分别作为碳源和氮源，通过水热法制备平均尺寸为 3.29nm 且量子产率为 19.6%的蓝色荧光碳量子点（b-CQDs）。新设计的 b-CQDs/核黄素比率荧光探针在 CIP 监测方面具有明显优势，与 CIP 相互作用时在 445nm 处的荧光强度显著增加，而在 510nm 处的强度保持稳定。在水体系中，荧光探针的 I/I 比值在 0-250μmol·L 的浓度范围内与 CIP 呈显著线性关系，探针的检测限低至 0.86μmol·L。b-CQDs 的出色选择性、宽检测范围、低检测限和高量子产率突出了它们在开发用于高效检测环丙沙星的先进传感探针方面的巨大潜力，为未来的传感器技术发展提供了有希望的见解。
