Karam Karam, Saleh Sarah, Chebbo Houssein, Jalloul Sarah, Fiani Elias
Department of Gastroenterology, Faculty of Medicine, University of Balamand, Beirut, Lebanon.
Faculty of Medicine, University of Balamand, Beirut, Lebanon.
Eur J Case Rep Intern Med. 2024 Jul 29;11(8):004673. doi: 10.12890/2024_004673. eCollection 2024.
Gastric carcinoid is a rare type of gastric malignancy accounting for around 7% of all gastrointestinal neuroendocrine tumours (NETs). While most gastric NETs (gNETs) are readily visible through direct visualisation by upper endoscopy, around 25% of gastric carcinoids are invisible because they are located in the submucosal gastric regions of the body and fundus. gNETs located in the intra-mucosal areas can be identified by gastric mapping; this can be done by taking random gastric biopsies from the antrum, body and fundus. We report a case of a well-differentiated gastric NET type 1 with atrophic gastritis diagnosed on upper endoscopy and pathological immunohistochemistry staining.
The case highlights that not all gNETs are visible under direct endoscopic visualisation.It is essential to understand the different types of gNETs.Understand that both type and size of gNETs impact therapeutic implications and prognosis.
胃类癌是一种罕见的胃恶性肿瘤，约占所有胃肠道神经内分泌肿瘤（NETs）的7%。虽然大多数胃NETs（gNETs）通过上消化道内镜直接观察很容易看到，但约25%的胃类癌是不可见的，因为它们位于胃体和胃底的黏膜下区域。位于黏膜内区域的gNETs可通过胃黏膜地图检查来识别；这可以通过从胃窦、胃体和胃底随机进行胃活检来完成。我们报告一例经上消化道内镜检查及病理免疫组化染色诊断为1型高分化胃NETs合并萎缩性胃炎的病例。
该病例强调并非所有gNETs在直接内镜观察下都可见。了解不同类型的gNETs很重要。要明白gNETs的类型和大小都会影响治疗意义和预后。
