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接受甲氧苄啶-磺胺甲恶唑预防类鼻疽的血液透析患者血流感染率较低。

Lower Rates of Bloodstream Infection in Patients on Hemodialysis Receiving Trimethoprim-Sulfamethoxazole Melioidosis Prophylaxis.

作者信息

Bryce Aliya, Davison Sara, Currie Bart J, Birrell Johanna M, Baird Robert W, Abeyaratne Asanga, Majoni Sandawana William, Brewster-O'Brien Teana, Tong Steven Y C

机构信息

Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Department of General Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

出版信息

Open Forum Infect Dis. 2024 Jul 31;11(8):ofae431. doi: 10.1093/ofid/ofae431. eCollection 2024 Aug.

Abstract

Hemodialysis is a risk factor for bloodstream infection (SAB). In this single-center study, SAB rates were 56% lower during the monsoonal wet season when patients on hemodialysis receive supervised melioidosis prophylaxis with trimethoprim-sulfamethoxazole. This intervention may reduce SAB rates in high-risk patients; however, further targeted studies are required.

摘要

血液透析是血流感染(SAB)的一个危险因素。在这项单中心研究中,当接受血液透析的患者在季风雨季接受复方新诺明预防类鼻疽的监督治疗时,SAB发生率降低了56%。这种干预措施可能会降低高危患者的SAB发生率;然而,还需要进一步的针对性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b89/11310582/ca52fdf870e7/ofae431_ga.jpg

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