S Haritha, Sudarsan Shyam Sudhakar, Anbarasan Subagar, Sankar Sakthimurugan
Department of Otorhinolaryngology, Head and Neck Surgery, Saveetha Medical College and Hospital, SIMATS, Saveetha University, Saveetha Nagar, Thandalam, Chennai, 602105 Tamil Nadu India.
Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3717-3721. doi: 10.1007/s12070-024-04719-3. Epub 2024 Apr 26.
Lymphomas are a diverse group of neoplastic disorders arising primarily in lymph nodes. They have been majorly classified into Hodgkin and Non-Hodgkin lymphomas(NHL). NHL can be of B, T and Null cell categories having further subtypes based on their histological characteristics. Lymphomas can be nodal and extra nodal. The head and neck area are the second most common site of extra nodal lymphoma, with tonsils being the most common site of involvement; other sites include the nasopharynx and tongue base. B- Cell type being the most common type. Predominantly occurs in elderly. Presentations depends on the site involved. Various modalities like surgical treatment, chemotherapy (or) radiotherapy is available. Each stage has varied survival rates and prognosis and responses to the treat depending on the patient factors. In this paper, we report two cases of patients with non-Hodgkin lymphoma of tonsil, where the preoperative clinical diagnosis and radiological diagnosis was inconclusive and final diagnosis was established based on histopathological examination.
淋巴瘤是一组主要起源于淋巴结的多种肿瘤性疾病。它们主要分为霍奇金淋巴瘤和非霍奇金淋巴瘤（NHL）。NHL可分为B细胞、T细胞和裸细胞类别，并根据其组织学特征进一步细分亚型。淋巴瘤可发生于淋巴结内和淋巴结外。头颈部是淋巴结外淋巴瘤的第二常见部位，扁桃体是最常受累的部位；其他部位包括鼻咽和舌根。B细胞型是最常见的类型。主要发生于老年人。临床表现取决于受累部位。有多种治疗方式，如手术治疗、化疗或放疗。根据患者因素，每个阶段的生存率、预后及对治疗的反应各不相同。在本文中，我们报告了2例扁桃体非霍奇金淋巴瘤患者，术前临床诊断和影像学诊断不明确，最终基于组织病理学检查确诊。
