Almishhadany Hashim S, Al Azzawi Asal A
General Practice, Emirates Health Services, Sharjah, ARE.
General Practice, University of Sharjah, Sharjah, ARE.
Cureus. 2025 Feb 6;17(2):e78628. doi: 10.7759/cureus.78628. eCollection 2025 Feb.
Non-Hodgkin lymphoma (NHL) is a diverse group of lymphoid malignancies, with varied clinical presentations depending on the anatomical site of involvement. Although typically presenting with nodal disease, extranodal manifestations are not uncommon. NHL involving Waldeyer's ring is considered rare, with the palatine tonsils being the most frequently affected location. This case report presents a 30-year-old male patient with bilateral tonsillar hypertrophy, ultimately diagnosed as NHL. The patient presented with a persistent sore throat, dysphagia, and snoring associated with sleep disturbances. Detailed physical examination, imaging studies, and histopathological analysis of the excised tonsillar tissue confirmed the diagnosis. This case underscores the importance of considering NHL in the differential diagnosis of persistent tonsillar enlargement to ensure timely and appropriate management.
非霍奇金淋巴瘤(NHL)是一组多样的淋巴系统恶性肿瘤,其临床表现因受累的解剖部位而异。虽然通常表现为淋巴结疾病,但结外表现也并不罕见。累及瓦尔代尔环的NHL被认为较为罕见,其中腭扁桃体是最常受累的部位。本病例报告介绍了一名30岁男性患者,其双侧扁桃体肥大,最终被诊断为NHL。该患者出现持续咽痛、吞咽困难以及与睡眠障碍相关的打鼾症状。详细的体格检查、影像学检查以及对切除的扁桃体组织进行的组织病理学分析证实了诊断。本病例强调了在持续性扁桃体肿大的鉴别诊断中考虑NHL的重要性,以确保及时且恰当的治疗。