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急性化脓性中耳炎伴面瘫的非典型表现:颞骨急性髓系白血病的髓外表现

Atypical Presentation of Acute Suppurative Otitis Media with Facial Palsy: Extra Medullary Manifestation of AML in Temporal Bone.

作者信息

Arora Ripu Daman, Nidhin S B, Nagarkar Nitin M, Banjare Amit Kumar

机构信息

Department of ENT & HNS, AIIMS Raipur, Raipur, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3693-3697. doi: 10.1007/s12070-024-04702-y. Epub 2024 Apr 26.

Abstract

Acute Myeloid Leukemia (AML) is the most common leukemia observed in the adult population, accounting for 80% of all leukemia cases. Extramedullary involvement in AML, where leukemic cells are found in organs or tissues outside the blood or bone marrow, is a rare occurrence [1]. The most frequent sites of extramedullary disease include the skin, central nervous system (CNS), and lymph nodes [2, 3]. In this case report, we present an instance of extramedullary AML in the temporal bone, which initially presented with symptoms such as earache, discharge, and facial asymmetry, mimicking acute suppurative otitis media with facial palsy. The patient underwent mastoid exploration and facial nerve decompression. A post-operative bone marrow biopsy confirmed the diagnosis of AML, leading to the initiation of chemotherapy. The patient is currently under follow-up care.

摘要

急性髓系白血病(AML)是成人中最常见的白血病,占所有白血病病例的80%。AML的髓外浸润是指在血液或骨髓以外的器官或组织中发现白血病细胞,这种情况很少见[1]。髓外疾病最常见的部位包括皮肤、中枢神经系统(CNS)和淋巴结[2,3]。在本病例报告中,我们呈现了一例颞骨髓外AML病例,该病例最初表现为耳痛、耳漏和面部不对称等症状,类似于伴有面神经麻痹的急性化脓性中耳炎。患者接受了乳突探查和面神经减压术。术后骨髓活检确诊为AML,随后开始化疗。该患者目前正在接受随访。

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