de Lima-Souza Reydson Alcides, Kimura Talita de Carvalho, Scarini João Figueira, Lavareze Luccas, Figueiredo-Maciel Tayná, Chone Carlos Takahiro, Egal Erika Said Abu, Altemani Albina, Mariano Fernanda Viviane
Department of Oral Diagnosis, Piracicaba Dental School, Universidade Estadual de Campinas (UNICAMP), Piracicaba, São Paulo Brazil.
Department of Pathology, School of Medical Sciences, Universidade Estadual de Campinas (UNICAMP), Rua Tessália Vieira de Camargo, 126, 13083-887 Campinas, São Paulo Brazil.
Indian J Otolaryngol Head Neck Surg. 2024 Aug;76(4):3604-3611. doi: 10.1007/s12070-024-04631-w. Epub 2024 Mar 25.
This study aimed to perform an integrative review of solitary angiokeratomas cases in the oral cavity and to report a new case in a 39-year-old man. A modified PECOS strategy was used using PubMed, Embase, Scopus, Web of Science databases, and the reference lists of the selected articles. Case reports of oral solitary angiokeratoma published in English, Portuguese, and Spanish languages with histopathological diagnosis without the presence of systemic disorders were included. Of the 51 articles identified, 18 met the eligibility criteria. Solitary angiokeratomas have a slight male predilection, with a peak incidence in the fourth decade of life. The tongue was the most common localization (77.7%), followed by buccal mucosa (11.1%), labial mucosa (5.6%), and tonsillar pillar (5.6%). The granulomatous appearance was the most frequent clinical aspect. Surgical excision was implemented in 94.4% of the cases. The lesion presented a good prognosis, with no recurrence in 3 to 24 months. In summary, solitary angiokeratoma is a rare lesion in the oral cavity. The professional making the oral diagnosis should be familiar with the clinical manifestation of angiokeratoma and be prepared to consider it in the differential diagnosis of pigmented lesions since these lesions may be part of systemic disorders.
The online version contains supplementary material available at 10.1007/s12070-024-04631-w.
本研究旨在对口腔孤立性血管角化瘤病例进行综合综述，并报告一例39岁男性的新病例。采用改良的PECOS策略，检索了PubMed、Embase、Scopus、Web of Science数据库以及所选文章的参考文献列表。纳入了以英文、葡萄牙文和西班牙文发表的、有组织病理学诊断且无全身性疾病的口腔孤立性血管角化瘤病例报告。在检索到的51篇文章中，18篇符合纳入标准。孤立性血管角化瘤略倾向于男性，发病高峰在生命的第四个十年。舌部是最常见的发病部位（77.7%），其次是颊黏膜（11.1%）、唇黏膜（5.6%）和扁桃体柱（5.6%）。肉芽肿样外观是最常见的临床特征。94.4%的病例采用了手术切除。病变预后良好，3至24个月内无复发。总之，孤立性血管角化瘤是口腔中的一种罕见病变。进行口腔诊断的专业人员应熟悉血管角化瘤的临床表现，并准备在色素沉着病变的鉴别诊断中考虑到它，因为这些病变可能是全身性疾病的一部分。
在线版本包含可在10.1〇〇7/s12〇7〇 - 〇24 - 〇4631 - w获取的补充材料。
