Keronen Joona, Huttunen Tuomas, Mennander Ari
Cardiothoracic Surgery, Tampere University Heart Hospital, Tampere, FIN.
Anesthesiology and Critical Care, Tampere University Heart Hospital, Tampere, FIN.
Cureus. 2024 Jul 10;16(7):e64285. doi: 10.7759/cureus.64285. eCollection 2024 Jul.
Background Arrhythmia after coronary artery bypass grafting (CABG) may occur immediately after the abrupt onset of reperfusion via all coronary bypass grafts simultaneously. We investigated whether early reperfusion of the left anterior descending coronary artery before weaning from cardiopulmonary bypass would decrease the frequency of early arrhythmias after CABG. We compared patients undergoing release of the left internal thoracic artery (LITA) graft flow before versus after aortic declamping during CABG. Methodology In total, 109 consecutive patients undergoing CABG were retrospectively analyzed. The heart rhythms after CABG of 46 patients with flow release from LITA before aortic declamping (study group) were compared with 63 patients with complete onset of reperfusion of all coronary bypass grafts simultaneously after aortic declamping (controls). Early arrhythmias were recorded and included atrial fibrillation, ventricular tachycardia, ventricular fibrillation, and arrhythmias necessitating temporary pacemaker support. Results Early arrhythmias occurred in seven out of 46 study group patients with the early release of LITA graft flow compared with 21 out of 63 controls (15.2% vs. 33.3%, p = 0.033). Creatine kinase-myocardial band levels were lower in the study group than in the controls (27.5 ± 58.4 vs. 33.0 ± 48.0, p = 0.004, respectively). Sinus rhythm was achieved in all but three patients before extubation including two in the study group and one in the controls. Conclusions The simple maneuver of releasing LITA graft flow before aortic declamping during CABG allows gradual reperfusion of the myocardium and may ensure early rhythm control.
背景 冠状动脉旁路移植术(CABG)后心律失常可能在所有冠状动脉旁路移植同时突然再灌注后立即发生。我们研究了在体外循环撤机前左前降支冠状动脉早期再灌注是否会降低CABG后早期心律失常的发生率。我们比较了CABG期间主动脉钳夹松开前与松开后接受左乳内动脉(LITA)移植血流释放的患者。
方法 总共对109例连续接受CABG的患者进行回顾性分析。将46例在主动脉钳夹松开前LITA血流释放的患者(研究组)CABG后的心律与63例在主动脉钳夹松开后所有冠状动脉旁路移植同时完全开始再灌注的患者(对照组)进行比较。记录早期心律失常,包括心房颤动、室性心动过速、心室颤动以及需要临时起搏器支持的心律失常。
结果 46例研究组患者中有7例在早期释放LITA移植血流后发生早期心律失常,而63例对照组中有21例发生(15.2%对33.3%,p = 0.033)。研究组肌酸激酶-心肌带水平低于对照组(分别为27.5±58.4对33.0±48.0,p = 0.004)。除3例患者外,所有患者在拔管前均恢复窦性心律,其中研究组2例,对照组1例。
结论 在CABG期间主动脉钳夹松开前释放LITA移植血流这一简单操作可使心肌逐渐再灌注,并可能确保早期心律控制。