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伴有复发性恶性胸腔积液的胸膜转移性黑色素瘤

Pleural Metastatic Melanoma With Recurrent Malignant Pleural Effusions.

作者信息

Prasad Sonal, Xiong Jay, Kaur Jasleen

机构信息

Internal Medicine, St. Joseph's Medical Center, Stockton, USA.

出版信息

Cureus. 2024 Jul 11;16(7):e64366. doi: 10.7759/cureus.64366. eCollection 2024 Jul.

DOI:10.7759/cureus.64366
PMID:39130922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11316843/
Abstract

Pleural metastatic melanoma is rare, and associated malignant pleural effusions are even rarer. We present a case of pleural metastatic melanoma with recurrent malignant pleural effusions. The initial diagnosis showed no metastatic disease, and the patient underwent resection and received a year of immunotherapy for localized disease. However, two years later, the patient presented with pleural metastatic melanoma with unresolving malignant pleural effusions requiring an indwelling pleural catheter and eventually, thoracotomy with decortication. Clinicians should have a high index of suspicion for pleural metastatic melanoma in the setting of recurrent pleural effusions, even though it is a rare occurrence.

摘要

胸膜转移性黑色素瘤罕见,而与之相关的恶性胸腔积液则更为罕见。我们报告一例伴有复发性恶性胸腔积液的胸膜转移性黑色素瘤病例。最初诊断未发现转移性疾病,患者接受了手术切除,并针对局限性疾病接受了一年的免疫治疗。然而,两年后,患者出现胸膜转移性黑色素瘤,伴有持续不消退的恶性胸腔积液,需要留置胸腔导管,最终接受了开胸剥脱术。临床医生在复发性胸腔积液的情况下,即使胸膜转移性黑色素瘤很少见,也应高度怀疑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/3bab01dd1f75/cureus-0016-00000064366-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/0a7d83e7735c/cureus-0016-00000064366-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/460083bcdc77/cureus-0016-00000064366-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/238a3fbfb8d7/cureus-0016-00000064366-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/26589c883a6b/cureus-0016-00000064366-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/3bab01dd1f75/cureus-0016-00000064366-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/0a7d83e7735c/cureus-0016-00000064366-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/460083bcdc77/cureus-0016-00000064366-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/238a3fbfb8d7/cureus-0016-00000064366-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/26589c883a6b/cureus-0016-00000064366-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a7/11316843/3bab01dd1f75/cureus-0016-00000064366-i05.jpg

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本文引用的文献

1
The Great Mimicker: Cutaneous Metastatic Melanoma Presenting as a Non-resolving Pleural Effusion.“伟大的模仿者”:表现为持续性胸腔积液的皮肤转移性黑色素瘤
Cureus. 2022 Aug 23;14(8):e28320. doi: 10.7759/cureus.28320. eCollection 2022 Aug.
2
Pleural Melanoma Metastasis.胸膜黑色素瘤转移。
Ann Thorac Surg. 2021 Aug;112(2):e103-e105. doi: 10.1016/j.athoracsur.2020.09.088. Epub 2021 Jan 7.
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Malignant pleural effusions: appropriate treatment approaches.恶性胸腔积液:恰当的治疗方法
Eurasian J Med. 2009 Dec;41(3):186-93.
4
Metastatic melanoma in the thorax: report of 130 patients.胸部转移性黑色素瘤:130例患者的报告。
AJR Am J Roentgenol. 1981 Aug;137(2):293-8. doi: 10.2214/ajr.137.2.293.