Aydin Yener, Turkyilmaz Atila, Intepe Yavuz Selim, Eroglu Atilla
Yozgat State Hospital, Department of Thoracic Surgery, Yozgat, Turkey.
Ataturk University, School of Medicine, Department of Thoracic Surgery, Erzurum, Turkey.
Eurasian J Med. 2009 Dec;41(3):186-93.
Malignant pleural effusion (MPE) is a common and important clinical condition. A complication in many types of tumors, its presence indicates the onset of the terminal stages of cancer. Dyspnea is the most common symptom of MPE. The most common underlying tumors are lymphomas and cancers of the lung, breast and ovaries, which account for 75% of cases. The diagnosis of MPE can be established by the presence of malignant cells in the pleural fluid or tissue. Median survival in these patients ranges from 3 to 12 months, with the shortest survival period presenting in lung cancer patients. The aim of MPE therapeutic approaches should be effective treatment and a short hospital stay. There are many different treatment options for patients who suffer from MPE, including serial thoracentesis, tube thoracostomy, pleurodesis, long term pleural catheter, pleuroperitoneal shunt, decortication, chemotherapy and radiotherapy. The choice of therapy is determined based on a patient's clinical situation as well as the underlying disease. Today, intercostal tube insertion and chemical pleurodesis are the most commonly prescribed treatment modalities.
恶性胸腔积液（MPE）是一种常见且重要的临床病症。它是多种肿瘤的并发症，其出现表明癌症已进入晚期。呼吸困难是MPE最常见的症状。最常见的原发肿瘤是淋巴瘤以及肺癌、乳腺癌和卵巢癌，这些肿瘤占病例的75%。MPE的诊断可通过在胸腔积液或组织中发现恶性细胞来确立。这些患者的中位生存期为3至12个月，其中肺癌患者的生存期最短。MPE治疗方法的目标应是有效治疗并缩短住院时间。对于患有MPE的患者有许多不同的治疗选择，包括连续胸腔穿刺术、胸腔置管引流、胸膜固定术、长期胸腔导管、胸膜腹膜分流术、胸膜剥脱术、化疗和放疗。治疗方法的选择是根据患者的临床情况以及基础疾病来决定的。如今，肋间置管和化学胸膜固定术是最常用的治疗方式。
