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英国一家三级医院肺癌手术后机器人辅助胸外科与电视辅助胸外科短期结局的比较:一项倾向匹配分析

A Comparison of Short-Term Outcomes of Robotic-Assisted Thoracic Surgery Versus Video-Assisted Thoracic Surgery Following Lung Cancer Surgery at a Tertiary Hospital in the United Kingdom: A Propensity-Matched Analysis.

作者信息

Mwesigwa Nicolas W, Tentzeris Vasileios

机构信息

Cardiothoracic Surgery, Hull University Teaching Hospitals NHS Trust, Hull, GBR.

Thoracic Surgery, Hull University Teaching Hospitals NHS Trust, Hull, GBR.

出版信息

Cureus. 2024 Jul 11;16(7):e64298. doi: 10.7759/cureus.64298. eCollection 2024 Jul.

Abstract

BACKGROUND

Robot-assisted thoracic surgery (RATS) is gaining popularity in lung resection surgeries; however, its quality outcome measures require further evaluation. This study compared the short-term perioperative outcomes of lung resection surgeries performed using RATS and video-assisted thoracic surgery (VATS) at a tertiary hospital in the UK.

METHODS

We performed a retrospective comparative analysis of 496 patients who underwent lung resection surgery at Castle Hill Hospital in the UK between January 2021 and April 2024. In the pre-matched cohort, 162 patients underwent RATS compared to 334 who underwent VATS. Using propensity matching based on the patient's forced expiratory volume in one second (FEV1) percentage of predicted age and body mass index (BMI), we included 324 patients in the analysis. Of these, 162 underwent RATS, and 162 underwent VATS, demonstrating satisfactory performance indicators.

RESULTS

The results from our analysis depicted that RATS had a significantly lower rate of prolonged air leak (≥7 minutes) than VATS (5.5% versus 7.1%, mean difference -1.32, 95% CI: -0.89-3.08, p = 0.034). RATS patients also had shorter duration of hospital stay (3.8 ± 4.1 days versus 4.7 ± 4.8, mean difference -0.901, 95% CI: -1.886-0.084; p = 0.073) and had more mediastinal lymph node dissections (39.5% versus 35.2%) than VATS. However, the proportion of patients who were upstaged after histopathological analysis of the resected lymph nodes was not different between the two groups. Furthermore, the groups had no significant differences regarding the infection rate, intermittent positive pressure ventilation (IPPV) use, and theatre return.

CONCLUSION

Robotic and video-assisted technologies produced equivalent results for the majority of the short-term outcomes evaluated. Additional research is necessary to confirm RATS's efficacy and determine its potential advantages over VATS for lung resection surgeries.

摘要

背景

机器人辅助胸外科手术(RATS)在肺切除手术中越来越受欢迎;然而,其质量结果指标需要进一步评估。本研究比较了英国一家三级医院使用RATS和电视辅助胸腔镜手术(VATS)进行肺切除手术的短期围手术期结果。

方法

我们对2021年1月至2024年4月在英国卡斯尔山医院接受肺切除手术的496例患者进行了回顾性比较分析。在预匹配队列中,162例患者接受了RATS手术,334例患者接受了VATS手术。基于患者的一秒用力呼气量(FEV1)占预测年龄和体重指数(BMI)的百分比进行倾向匹配后,我们纳入了324例患者进行分析。其中,162例接受了RATS手术,162例接受了VATS手术,显示出令人满意的性能指标。

结果

我们的分析结果表明,RATS的长时间漏气(≥7分钟)发生率显著低于VATS(5.5%对7.1%,平均差异-1.32,95%CI:-0.89 - 3.08,p = 0.034)。RATS组患者的住院时间也更短(3.8±4.1天对4.7±4.8天,平均差异-0.901,95%CI:-1.886 - 0.084;p = 0.073),并且比VATS组有更多的纵隔淋巴结清扫(39.5%对35.2%)。然而,两组在切除淋巴结的组织病理学分析后分期上调的患者比例没有差异。此外,两组在感染率、间歇正压通气(IPPV)使用和返回手术室方面没有显著差异。

结论

机器人技术和电视辅助技术在大多数评估的短期结果方面产生了等效的结果。需要进一步的研究来证实RATS的疗效,并确定其在肺切除手术中相对于VATS的潜在优势。

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