Bhatia Mannat K, Dastagir Fatima, Khan Abdul M, Redel Henry
Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School, Saint Peter's University Hospital, New Brunswick, USA.
Department of Internal Medicine, St. George's University School of Medicine, Saint Peter's University Hospital, New Brunswick, USA.
Cureus. 2024 Jul 10;16(7):e64234. doi: 10.7759/cureus.64234. eCollection 2024 Jul.
Shigellosis, a significant public health concern, has increasingly been recognized as a sexually transmitted infection (STI) among men who have sex with men (MSM), particularly in those with HIV. This case report describes a 25-year-old MSM with advanced HIV who presented with recurrent multidrug-resistant (MDR) infection despite multiple hospitalizations and antibiotic courses. The patient's high-risk sexual behaviors and suboptimal HIV management likely contributed to recurrent exposure to and the selection of resistant strains. This case highlights the complex interplay of individual behaviors, immune suppression, antimicrobial resistance, and the healthcare system in the context of this emerging STI. It underscores the importance of optimized HIV care, comprehensive patient education, robust healthcare coordination, and strengthened surveillance to effectively combat MDR shigellosis in vulnerable populations.
志贺菌病是一个重大的公共卫生问题，越来越多地被认为是男男性行为者（MSM）中的一种性传播感染（STI），尤其是在感染艾滋病毒的人群中。本病例报告描述了一名25岁的晚期艾滋病毒感染男男性行为者，尽管多次住院并接受了抗生素治疗，但仍反复出现多重耐药（MDR）感染。患者的高危性行为和不理想的艾滋病毒管理可能导致反复接触并选择耐药菌株。该病例突出了在这种新兴性传播感染背景下个体行为、免疫抑制、抗菌药物耐药性和医疗保健系统之间的复杂相互作用。它强调了优化艾滋病毒护理、全面的患者教育、强有力的医疗保健协调以及加强监测对于有效对抗弱势群体中的多重耐药志贺菌病的重要性。
