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Nutrients. 2020 Dec 28;13(1):64. doi: 10.3390/nu13010064.
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Prevalence and risk factors of sarcopenia in community-dwelling older adults visiting regional medical institutions from the Kadoma Sarcopenia Study.来自《神户肌少症研究》的社区居住老年人群体到区域医疗机构就诊的肌少症患病率及其危险因素。
Sci Rep. 2020 Nov 5;10(1):19129. doi: 10.1038/s41598-020-76185-0.
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Effects of astaxanthin on the protection of muscle health (Review).虾青素对肌肉健康的保护作用（综述）。
Exp Ther Med. 2020 Oct;20(4):2941-2952. doi: 10.3892/etm.2020.9075. Epub 2020 Jul 29.
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The prevalence and factors associated with sarcopenia among community living elderly with type 2 diabetes mellitus in primary care clinics in Malaysia.马来西亚基层医疗诊所中 2 型糖尿病社区老年患者肌少症的患病率及相关因素。
PLoS One. 2020 May 20;15(5):e0233299. doi: 10.1371/journal.pone.0233299. eCollection 2020.
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Prevalence and Risk Factors Governing the Loss of Muscle Function in Elderly Sarcopenia Patients: A longitudinal Study in China with 4 Years of Follow-Up.中国一项为期 4 年的纵向研究：老龄化肌少症患者肌肉功能丧失的流行率及相关影响因素。
J Nutr Health Aging. 2020;24(5):518-524. doi: 10.1007/s12603-020-1361-0.
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Android to gynoid fat ratio and its association with functional capacity in male patients with heart failure.男性心力衰竭患者的安卓体脂比及其与功能能力的关系。
ESC Heart Fail. 2020 Jun;7(3):1101-1108. doi: 10.1002/ehf2.12657. Epub 2020 Mar 27.
8
Android Fat Deposition and Its Association With Cardiovascular Risk Factors in Overweight Young Males.超重年轻男性的安卓型脂肪沉积及其与心血管危险因素的关联。
Front Physiol. 2019 Sep 18;10:1162. doi: 10.3389/fphys.2019.01162. eCollection 2019.
9
Prevalence of sarcopenia and related factors in community-dwelling elderly individuals.社区居住老年人中肌肉减少症的患病率及相关因素
Saudi Med J. 2019 May;40(6):568-574. doi: 10.15537/smj.2019.6.23917.
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Android fat as a determinant of metabolic syndrome: Sex differences.安卓体脂与代谢综合征的相关性：性别差异。
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安卓系统（ANDROID）和白蛋白/球蛋白比值（A/G ratio）与2型糖尿病患者的肌肉减少症相关。

ANDROID and A/G ratio are correlated with sarcopenia among type 2 diabetes patients.

作者信息

Zhang Dongxiao, Li Chen, Hu Wenchao, He Lanjie

机构信息

Department of Endocrinology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, China.

Department of Endocrinology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Shibei District, Qingdao 266035, Shandong, China.

出版信息

Ther Adv Endocrinol Metab. 2024 Aug 7;15:20420188241269181. doi: 10.1177/20420188241269181. eCollection 2024.

DOI:10.1177/20420188241269181
PMID:39131663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11311146/
Abstract

BACKGROUND

Fat distribution plays an important role in impaired glucose tolerance. Android adiposity (ANDROID) and gynoid adiposity (GYNOID) have been proven to be linked with insulin resistance. A higher risk of sarcopenia is associated with type 2 diabetes mellitus (T2DM). In this study, ANDROID, GYNOID, and ANDROID to GYNOID ratios (A/G ratios) were evaluated in T2DM patients to determine if they were associated with sarcopenia.

METHODS

We recruited 1086 T2DM patients, measured skeletal muscle index (SMI), ANDROID, GYNOID, and collected clinical data.

RESULTS

T2DM patients with 119 male subjects had sarcopenia (20.24%), and 72 female subjects had sarcopenia (16.51%). All patients with T2DM who had high ANDROID and A/G ratios were at a reduced risk of sarcopenia. The SMI showed a correlation with ANDROID and A/G ratios among subjects with T2DM.

CONCLUSION

ANDROID and A/G ratios are inversely related to sarcopenia in T2DM patients.

摘要

背景

脂肪分布在糖耐量受损中起重要作用。已证实腹型肥胖（ANDROID）和臀型肥胖（GYNOID）与胰岛素抵抗有关。2型糖尿病（T2DM）患者发生肌肉减少症的风险更高。在本研究中，对T2DM患者的ANDROID、GYNOID以及ANDROID与GYNOID比值（A/G比值）进行评估，以确定它们是否与肌肉减少症相关。

方法

我们招募了1086例T2DM患者，测量骨骼肌指数（SMI）、ANDROID、GYNOID，并收集临床数据。

结果

119例男性T2DM患者存在肌肉减少症（20.24%），72例女性患者存在肌肉减少症（16.51%）。所有ANDROID和A/G比值高的T2DM患者发生肌肉减少症的风险降低。在T2DM患者中，SMI与ANDROID和A/G比值相关。

结论

在T2DM患者中，ANDROID和A/G比值与肌肉减少症呈负相关。