Suppr超能文献

马来西亚基层医疗诊所中 2 型糖尿病社区老年患者肌少症的患病率及相关因素。

The prevalence and factors associated with sarcopenia among community living elderly with type 2 diabetes mellitus in primary care clinics in Malaysia.

机构信息

Department of Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia.

Malaysian Research Institute on Ageing, Universiti Putra Malaysia, Serdang, Malaysia.

出版信息

PLoS One. 2020 May 20;15(5):e0233299. doi: 10.1371/journal.pone.0233299. eCollection 2020.

Abstract

Sarcopenia is a recognised geriatric syndrome but few studies address its associated factors among elderly with type 2 diabetes mellitus (T2DM) in South East Asia. This study aimed to determine the prevalence of sarcopenia and its associated factors among the elderly with T2DM in public primary care clinics in Malaysia. This study utilised data from a longitudinal study of 506 adults with T2DM aged ≥60 years. Data on socio-demography, clinical and functional status, diet and levels of physical activity (PA) were collected. Sarcopenia was defined using Asian Working Group for Sarcopenia criteria and its associated factors were analysed using multiple logistic regression. The proportion of elderly with T2DM with sarcopenia was 28.5%. Those aged ≥70 years (β = 0.73;OR = 2.07; 95%CI = 1.24, 3.48; p = 0.006), men (β = 0.61; OR = 1.84; 95%CI = 1.12, 3.02; p = 0.017), with ≥10 years duration of diabetes (β = 0.62; OR = 1.85; 95%CI = 1.11, 3.09; p = 0.018), not using insulin sensitizers (β = -1.44; OR = 0.24; 95%CI = 0.08, 0.71; p = 0.010), using less than 5 medications (β = 0.68; OR = 1.98; 95%CI = 1.17, 3.36; p = 0.011), low body mass index (BMI) (β = -2.43; OR = 0.09; 95%CI = 0.05, 0.17; p<0.001), and engaging in low (β = 0.77; OR = 2.15; 95%CI = 1.07, 4.35; p = 0.032) and moderate physical activities (β = 0.80; OR = 2.23; 95%CI = 1.07, 4.66; p = 0.033) were associated with sarcopenia. Factors that predicts sarcopenia such as level of physical activity and body mass index were among the modifiable factors that could be used in developing future strategies to prevent or delay the progression of sarcopenia among elderly with T2DM to improve their health status.

摘要

肌少症是一种公认的老年综合征,但在东南亚,很少有研究关注 2 型糖尿病(T2DM)老年患者的相关因素。本研究旨在确定马来西亚公立初级保健诊所中 T2DM 老年患者肌少症的患病率及其相关因素。本研究利用了一项针对 506 名年龄≥60 岁的 T2DM 成年人的纵向研究的数据。收集了社会人口统计学、临床和功能状态、饮食和身体活动(PA)水平的数据。使用亚洲肌少症工作组标准定义肌少症,并使用多因素逻辑回归分析其相关因素。患有 T2DM 的老年患者中肌少症的比例为 28.5%。年龄≥70 岁(β=0.73;OR=2.07;95%CI=1.24,3.48;p=0.006)、男性(β=0.61;OR=1.84;95%CI=1.12,3.02;p=0.017)、糖尿病病程≥10 年(β=0.62;OR=1.85;95%CI=1.11,3.09;p=0.018)、未使用胰岛素增敏剂(β=-1.44;OR=0.24;95%CI=0.08,0.71;p=0.010)、使用少于 5 种药物(β=0.68;OR=1.98;95%CI=1.17,3.36;p=0.011)、低体重指数(BMI)(β=-2.43;OR=0.09;95%CI=0.05,0.17;p<0.001)和进行低(β=0.77;OR=2.15;95%CI=1.07,4.35;p=0.032)和中度体力活动(β=0.80;OR=2.23;95%CI=1.07,4.66;p=0.033)与肌少症相关。身体活动水平和体重指数等预测肌少症的因素是可用于制定未来策略的可改变因素之一,这些策略可用于预防或延缓 T2DM 老年患者肌少症的进展,以改善他们的健康状况。

相似文献

7
Risk Factors for Sarcopenia in the Elderly with Type 2 Diabetes Mellitus and the Effect of Metformin.
J Diabetes Res. 2020 Oct 7;2020:3950404. doi: 10.1155/2020/3950404. eCollection 2020.
9
Alternative skeletal muscle index for sarcopenia diagnosis in elderly patients with type 2 diabetes mellitus: A pilot study.
Front Endocrinol (Lausanne). 2023 Feb 9;14:1083722. doi: 10.3389/fendo.2023.1083722. eCollection 2023.

引用本文的文献

3
5
Nutritional Approach to Diabetic Sarcopenia: A Comprehensive Review.
Curr Nutr Rep. 2025 Mar 19;14(1):48. doi: 10.1007/s13668-025-00637-0.
6
Prevalence of Malnutrition and Associated Factors Among the Elderly With Type 2 Diabetes Using MNA Form.
J Nutr Metab. 2025 Mar 5;2025:2107146. doi: 10.1155/jnme/2107146. eCollection 2025.
10
Prevalence and risk factors of osteosarcopenia in elderly patients with uncontrolled type 2 diabetes.
Endocrine. 2025 Jan;87(1):59-66. doi: 10.1007/s12020-024-04001-0. Epub 2024 Aug 19.

本文引用的文献

2
Polypharmacy and sarcopenia in hospitalized older patients: results of the GLISTEN study.
Aging Clin Exp Res. 2019 Apr;31(4):557-559. doi: 10.1007/s40520-019-01136-3. Epub 2019 Feb 18.
3
Sarcopenia: revised European consensus on definition and diagnosis.
Age Ageing. 2019 Jan 1;48(1):16-31. doi: 10.1093/ageing/afy169.
4
Association of diabetic retinopathy with both sarcopenia and muscle quality in patients with type 2 diabetes: a cross-sectional study.
BMJ Open Diabetes Res Care. 2017 May 27;5(1):e000404. doi: 10.1136/bmjdrc-2017-000404. eCollection 2017.
5
Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis.
Clin Interv Aging. 2017 May 17;12:835-845. doi: 10.2147/CIA.S132940. eCollection 2017.
8
Frailty and Sarcopenia as Predictors of Adverse Health Outcomes in Persons With Diabetes Mellitus.
J Am Med Dir Assoc. 2016 Sep 1;17(9):846-51. doi: 10.1016/j.jamda.2016.07.007.
10
Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia.
J Am Med Dir Assoc. 2014 Feb;15(2):95-101. doi: 10.1016/j.jamda.2013.11.025.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验