Jones Andrew
Can J Health Hist. 2023 Apr;40(1):33-64. doi: 10.3138/cjhh.594-062022. Epub 2023 May 31.
In 1962, Ontario's Addiction Research Foundation launched the first double-blind randomized controlled trial of LSD therapy as a treatment for alcoholism. The study, which found that LSD was not effective, was heavily criticized by other therapists working with the drug. These critics argued that the Toronto researchers who carried out the study were biased against LSD and used an anti-therapeutic method that was destined to produce negative results. Instead of creating a comfortable and supportive environment, they stressed, the Toronto group restrained patients to a bed in a hospital ward, used an unusually large dose of LSD, and hardly provided any careful therapeutic support. Some even compared this method to a "form of torture." Historians have paid little attention to the study, mentioning it only as an example of flawed or naïve LSD therapy that contrasted with the more advanced "psychedelic" approach developed in Saskatchewan. In this paper, I take a closer look at the Toronto psychiatrists who carried out the study and created the unique method that was employed. I show that they were actually quite excited about LSD and were more sophisticated in their approach to its use than has been appreciated by historians and critics. In many ways, they had their own brand of LSD expertise that differed from that of the Saskatchewan group. Some of the problems with the ARF study, then, did not stem from negative bias or a lack of competency, but instead resulted from the awkward relationship between LSD therapy and controlled trials.
1962年,安大略省成瘾研究基金会发起了第一项将LSD疗法作为治疗酗酒方法的双盲随机对照试验。该研究发现LSD无效,受到了其他使用该药物的治疗师的严厉批评。这些批评者认为,进行这项研究的多伦多研究人员对LSD有偏见,采用了一种注定会产生负面结果的反治疗方法。他们强调,多伦多研究团队没有营造一个舒适且支持性的环境,而是将患者限制在医院病房的床上,使用了异常大剂量的LSD,并且几乎没有提供任何细致的治疗支持。有些人甚至将这种方法比作“一种折磨形式”。历史学家很少关注这项研究,只是将其作为有缺陷或幼稚的LSD疗法的一个例子提及,与萨斯喀彻温省开发的更先进的“迷幻”方法形成对比。在本文中,我更深入地研究了进行这项研究并创造了所采用的独特方法的多伦多精神病医生。我表明,他们实际上对LSD相当兴奋,并且在使用方法上比历史学家和批评者所认为的更为成熟。在许多方面,他们有自己独特的LSD专业知识,与萨斯喀彻温省的团队不同。因此,成瘾研究基金会的这项研究存在的一些问题并非源于负面偏见或能力不足,而是源于LSD疗法与对照试验之间的尴尬关系。