Naval Medical Center of PLA, Naval Medical University, Shanghai, 200433, China.
Key Laboratory of Molecular Neurobiology of Ministry of Education, Naval Medical University, Shanghai, 200433, China.
Sci Rep. 2024 Aug 12;14(1):18668. doi: 10.1038/s41598-024-69242-5.
Under total sleep deprivation, both inhibitory and motor control are impaired. However, how circadian rhythm sleep loss caused by irregular sleep pattern affects motor inhibition and execution in continuous actions remains unknown. This study utilized a pointing task to investigate the question over 30 days. During regular trials, participants were instructed to tap on a specified location, while in countermanding trials, they were required to countermand their current action. Additionally, there was a control group performed the same task following a normal 24-h rhythm. The results indicated that the decrease in accuracy and the increase in movement time in countermanding trials were more prominent in the shift work group. In contrast, there was no significant difference in reaction time between the two groups. Notably, the shift work group outperformed the control group in terms of movement time in regular trials and radial displacement in countermanding trials. Overall, these results show that circadian rhythm sleep loss predominantly affects inhibitory control, rather than motor control, underscoring the nuanced impacts of sleep disruption on differential aspects of cognitive and motor functions.
在完全睡眠剥夺的情况下，抑制和运动控制都会受到损害。然而，不规则睡眠模式导致的昼夜节律睡眠缺失如何影响连续动作中的运动抑制和执行，目前尚不清楚。本研究通过一个指向任务在 30 多天的时间里对此问题进行了调查。在常规试验中，参与者被指示点击指定位置，而在反命令试验中，他们需要取消当前的动作。此外，还有一个对照组按照正常的 24 小时节律执行相同的任务。结果表明，在轮班工作组中，反命令试验的准确性下降和运动时间增加更为明显。相比之下，两组的反应时间没有显著差异。值得注意的是，轮班工作组在常规试验中的运动时间和反命令试验中的放射状位移方面优于对照组。总的来说，这些结果表明，昼夜节律睡眠缺失主要影响抑制控制，而不是运动控制，突出了睡眠中断对认知和运动功能不同方面的细微影响。
