Kołodziejczak Anna, Rotsztejn Helena
Chair of Cosmetology, Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Lódź, Łódź, Poland.
J Cosmet Laser Ther. 2024 Nov 16;26(5-8):94-102. doi: 10.1080/14764172.2024.2390584. Epub 2024 Aug 13.
The purpose of this study was to assess changes in skin elasticity and other skin defects related to the aging of skin around eyes following the use of combination treatment carboxytherapy and chemical peels (ferulic acid combined with ascorbic acid, lactobionic acid).
A total of 39 Caucasian patients were subjected to a series of five combination carboxytherapy and chemical peels treatments at weekly intervals. The Cutometer device was used to objectively measure skin elasticity. The assessment was supplemented by photographic documentation.
A statistically significant improvement in skin elasticity assessed on the basis of R2 and R7 parameters ( < .0001, = .001, respectively) was demonstrated after a series of five sessions of carboxytherapy combined with chemical peels. The improvement in the R2 parameter was observed in 82.1%, while R7 in 76.9% of study participants. It observed that the number of participants who benefited from treatment with ferulic acid and ascorbic acid was statistically higher compared with the second group ( = .036). Improved R2 values were reported in 100% of participants undergoing carboxytherapy combined with ferulic and ascorbic acid.
Carboxytherapy in combination with chemical peels improved skin elasticity and can be used to reduce other skin defects.
本研究旨在评估联合应用羧基疗法和化学换肤术（阿魏酸联合抗坏血酸、乳糖酸）后，眼周皮肤老化相关的皮肤弹性变化及其他皮肤缺陷。
共有39名白种人患者接受了一系列每周一次的五次羧基疗法和化学换肤术联合治疗。使用皮肤弹性测定仪客观测量皮肤弹性。评估辅以摄影记录。
在进行了一系列五次羧基疗法联合化学换肤术后，基于R2和R7参数评估的皮肤弹性有统计学显著改善（分别为<0.0001，=0.001）。82.1%的研究参与者观察到R2参数有所改善，而76.9%的参与者观察到R7参数有所改善。观察到与第二组相比，从阿魏酸和抗坏血酸治疗中获益的参与者数量在统计学上更高（=0.036）。在接受羧基疗法联合阿魏酸和抗坏血酸治疗的所有参与者中均报告了R2值的改善。
羧基疗法联合化学换肤术可改善皮肤弹性，并可用于减少其他皮肤缺陷。
