Farsi Soroush, Held Michael, Brannon Madalyn, Eckard Peter, King Deanne, Vural Emre, Sunde Jumin, Moreno Mauricio
Otolaryngology - Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, USA.
Cureus. 2024 Jul 13;16(7):e64467. doi: 10.7759/cureus.64467. eCollection 2024 Jul.
Background This study aimed to identify outcome predictors with the GEM microvascular coupler system (GEM Coupler) in a series of patients undergoing free flap reconstruction for head and neck defects. Methodology In this retrospective chart review of 218 consecutive microvascular procedures performed on 204 patients at an academic tertiary care center, demographics, comorbidities, surgical data, and outcomes were retrieved. The endpoints for the analysis were microvascular revision surgery and flap survival. Results The study included 142 (70.2%) males and 62 (29.8%) females, with a mean age of 56 years, primarily treated for malignancy (76%). The anterolateral thigh and fibula were the most commonly used flaps (40.4% and 27.1%, respectively). In 21 (9.6%) cases, a double venous anastomosis was performed. There were nine flap failures requiring microvascular revision surgery; the flap was salvaged in four of these cases yielding an overall success rate of 97.7%. Factors associated with total flap loss included a history of a thrombotic or embolic event (p = 0.017), deep circumflex iliac artery flap (p < 0.001), and absence of monitoring skin paddle (p < 0.001). Conclusions Prothrombotic conditions, buried flaps, and flap type are outcome predictors in patients undergoing microvascular reconstruction with GEM Coupler.
背景 本研究旨在确定在一系列接受头颈部缺损游离皮瓣重建的患者中,使用GEM微血管吻合器系统(GEM吻合器)的预后预测因素。方法 在一所学术性三级医疗中心对204例患者连续进行的218例微血管手术进行回顾性病历审查,收集人口统计学、合并症、手术数据和预后情况。分析的终点是微血管修复手术和皮瓣存活情况。结果 该研究纳入了142例(70.2%)男性和62例(29.8%)女性,平均年龄56岁,主要治疗恶性肿瘤(76%)。股前外侧皮瓣和腓骨皮瓣是最常用的皮瓣(分别为40.4%和27.1%)。21例(9.6%)患者进行了双静脉吻合。有9例皮瓣失败需要进行微血管修复手术;其中4例皮瓣得以挽救,总体成功率为97.7%。与皮瓣完全丢失相关的因素包括有血栓形成或栓塞事件史(p = 0.017)、旋髂深动脉皮瓣(p < 0.001)以及无监测皮岛(p < 0.001)。结论 血栓前状态、隐匿皮瓣和皮瓣类型是使用GEM吻合器进行微血管重建患者的预后预测因素。